Opioids are a mainstay of acute pain management but can have many adverse effects,
contributing to problematic long-term use. Opioid tolerance (increased dose needed for …

Worldwide, the use of prescription opioid analgesics more than doubled between 2001 and
2013, with several countries, including the USA, Canada, and Australia, experiencing …

This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

Stigma as a fundamental hindrance to the United States opioid overdose crisis response |
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Background One in 16 surgical patients prescribed opioids becomes a long-term user.
Overprescribing opioids after surgery is common, and the lack of multidisciplinary procedure …

Enhanced recovery after surgery (ERAS) programmes are increasingly becoming standard
of care for several surgical procedures. However, compliance with ERAS protocols including …

Clinical decision making needs to be supported by evidence that treatments are beneficial to
individual patients. Although randomized control trials (RCTs) are the gold standard for …

Background Inadequate pain management after surgery increases the risk of postoperative
complications and may predispose for chronic postsurgical pain. Perioperative ketamine …

Surgical procedures are key drivers of pain development and opioid utilization globally.
Various organizations have generated guidance on postoperative pain management …

Importance Risk of opioid use disorder, overdose, and death from prescription opioids
increases as dosage, duration, and use of extended-release and long-acting formulations …