Microfluidic lab-on-a-chip provides a new platform with unique advantages to mimic
complex physiological microenvironments in vivo and has been increasingly exploited to …

Human pluripotent stem cells (hPSCs) are a promising source of cells for cell replacement-
based therapies as well as modeling human development and diseases in vitro. However …

Inoculation of single cells into separate culture chambers is one of the key requirements in
single-cell analysis. This paper reports an innovative microfluidic chip integrating two …

Microfluidic devices are used for various applications in biology and medicine. From on-chip
modelling of human organs for drug screening and fast and straightforward point-of-care …

The field of microbiology have traditionally been concerned with and focused on studies at
the population level. Microfluidic platforms have emerged as important tools for biology …

Microfluidic devices employ submillimeter length scale control of flow to achieve high-
resolution spatial and temporal control over the microenvironment, providing powerful tools …

Recently, single cell cloning techniques have been gradually developed benefited from their
important roles in monoclonal antibody screening, tumor heterogeneity research fields, etc …

Embryogenesis is a highly regulated developmental process requiring complex mechanical
and biochemical microenvironments to give rise to a fully developed and functional embryo …

Secreted signals originate from a given cell or group of cells and diffuse through the
extracellular space. These signals consist of cytokines and growth factors and are defined …

Single-cell cloning (SCC) is a critical step in generating monoclonal cell lines, which are
widely used as in vitro models and for producing proteins with high reproducibility for …