Swine is biologically one of the most relevant large animal models for biomedical research.
With its use as food animal that can be exploited as a free cell and tissue source for research …

In pigs, the major histocompatibility complex (MHC), or swine leukocyte antigen (SLA)
complex, maps to Sus scrofa chromosome 7. It consists of three regions, the class I and …

Classical approaches to African swine fever virus (ASFV) vaccine development have not
been successful; inactivated virus does not provide protection and use of live attenuated …

African swine fever (ASF) is a lethal haemorrhagic disease of domestic pigs for which there
is no vaccine. Strains of the virus with reduced virulence can provide protection against …

T cells are an essential component of the adaptive immune system. Over the last 15 years, a
constantly growing toolbox with which to study T cell biology in pigs has allowed detailed …

We have used the pig, a large natural host animal for influenza with many physiological
similarities to humans, to characterize αβ, γδ T cell and antibody (Ab) immune responses to …

African swine fever virus is currently present in all of the world's continents apart from
Antarctica, and efforts to control the disease are hampered by the lack of a commercially …

Influenza viruses are an ongoing threat to humans and are endemic in pigs, causing
considerable economic losses to farmers. Pigs are also a source of new viruses potentially …

For the first time we have defined naïve, central memory, effector memory and differentiated
effector porcine CD8 T cells and analyzed their distribution in lymphoid and respiratory …

Abstract γδ T cells constitute a major portion of lymphocytes in the blood of both ruminants
and swine. Subpopulations of swine γδ T cells have been distinguished by CD2 and CD8α …