BACKGROUND Within the antral follicle, the oocyte is reliant on metabolic support from its
surrounding somatic cells. Metabolism plays a critical role in oocyte developmental …

Metabolism and ATP levels within the oocyte and adjacent cumulus cells are associated
with quality of oocyte and optimal development of a healthy embryo. Lipid metabolism …

Fatty acids (FAs) provide cellular energy under starvation, yet how they mobilize and move
into mitochondria in starved cells, driving oxidative respiration, is unclear. Here, we clarify …

Maintaining cellular lipid homeostasis is crucial to oxidative tissues, and it becomes
compromised in obesity. Lipid droplets (LD) play a central role in lipid homeostasis by …

Lipid droplets (LDs) are independent organelles that are composed of a lipid ester core and
a surface phospholipid monolayer. Recent studies have revealed many new proteins …

Lipid droplets (LDs) store lipids and hence serve as energy reservoir and as a source for
building-blocks for the organelle membrane systems. LD biology therefore depends on tight …

This review considers how our understanding of preimplantation embryo metabolism has
progressed since the pioneering work on this topic in the late 1960s and early 1970s …

Triacylglycerol (TG) is a storage lipid which serves as an energy reservoir and a source of
signalling molecules and substrates for membrane biogenesis. TG is essential for many …

Mammalian oocytes and early cleavage-stage embryos are critically dependent on their~
100,000 mitochondria to develop from ovulation to compacted morula stage. They rely …

Lipid droplets are the least characterized of cellular organelles. Long considered simple
lipid storage depots, these dynamic and remarkable organelles have recently been …