mRNA m6A detection
S Moshitch-Moshkovitz, M Sevilla-Sharon… - Nature Reviews …, 2024 - nature.com
Abstract N 6-methyladenosine (m 6 A) is the most prevalent internal mRNA modification.
Recent research has highlighted its role as a key regulator of gene expression, influencing …
Recent research has highlighted its role as a key regulator of gene expression, influencing …
Poised PABP–RNA hubs implement signal-dependent mRNA decay in development
Signaling pathways drive cell fate transitions largely by changing gene expression.
However, the mechanisms for rapid and selective transcriptome rewiring in response to …
However, the mechanisms for rapid and selective transcriptome rewiring in response to …
Budding yeast as an ideal model for elucidating the role of N6‐methyladenosine in regulating gene expression
WS Albihlal, WY Chan, FJ van Werven - Yeast, 2024 - Wiley Online Library
Abstract N6‐methyladenosine (m6A) is a highly abundant and evolutionarily conserved
messenger RNA (mRNA) modification. This modification is installed on RRACH motifs on …
messenger RNA (mRNA) modification. This modification is installed on RRACH motifs on …
The yeast RNA methylation complex consists of conserved yet reconfigured components with m6A-dependent and independent roles
I Ensinck, A Maman, WS Albihlal, M Lassandro… - Elife, 2023 - elifesciences.org
Abstract N6-methyladenosine (m6A), the most abundant mRNA modification, is deposited in
mammals/insects/plants by m6A methyltransferase complexes (MTC) comprising a catalytic …
mammals/insects/plants by m6A methyltransferase complexes (MTC) comprising a catalytic …
Positional motif analysis reveals the extent of specificity of protein-RNA interactions observed by CLIP
Background Crosslinking and immunoprecipitation (CLIP) is a method used to identify in
vivo RNA–protein binding sites on a transcriptome-wide scale. With the increasing amounts …
vivo RNA–protein binding sites on a transcriptome-wide scale. With the increasing amounts …
Vir1p, the yeast homolog of virilizer, is required for mRNA m6A methylation and meiosis
Abstract N6-Methyladenosine (m6A) is among the most abundant modifications of
eukaryotic mRNAs. mRNA methylation regulates many biological processes including …
eukaryotic mRNAs. mRNA methylation regulates many biological processes including …
m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations
N6-methyladenosine (m6A) is a widely studied and abundant RNA modification. The m6A
mark regulates the fate of RNAs in various ways, which in turn drives changes in cell …
mark regulates the fate of RNAs in various ways, which in turn drives changes in cell …
Towards in silico CLIP-seq: predicting protein-RNA interaction via sequence-to-signal learning
M Horlacher, N Wagner, L Moyon, K Kuret, N Goedert… - Genome biology, 2023 - Springer
We present RBPNet, a novel deep learning method, which predicts CLIP-seq crosslink count
distribution from RNA sequence at single-nucleotide resolution. By training on up to a million …
distribution from RNA sequence at single-nucleotide resolution. By training on up to a million …
Kar4, the yeast homolog of METTL14, is required for mRNA m6A methylation and meiosis
ZM Park, AJ Sporer, K Kraft, KK Lum, E Blackman… - PLoS …, 2023 - journals.plos.org
KAR4, the yeast homolog of the mammalian mRNA N6A-methyltransferase complex
component METTL14, is required for two disparate developmental programs in …
component METTL14, is required for two disparate developmental programs in …
Phylogenetic and functional analyses of N6-methyladenosine RNA methylation factors in the wheat scab fungus Fusarium graminearum
ABSTRACT In eukaryotes, N 6-methyladenosine (m6A) RNA modification plays a crucial
role in governing the fate of RNA molecules and has been linked to various developmental …
role in governing the fate of RNA molecules and has been linked to various developmental …