Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …

Cancer stem cells (CSCs) are a vital subpopulation of cells to target for the treatment of
cancers. In oesophageal squamous cell carcinoma (ESCC), there are several markers such …

The Wnt/β-catenin pathway has important roles in chemoresistance and multidrug
resistance 1 (MDR1) expression in some cancers, but its involvement in breast cancer and …

Only 10% of cancer-related deaths result from primary tumors; most are caused by
metastatic tumors. It is believed that the metastatic power of tumor cells is attributed to …

Background MicroRNAs are regulators that can play an essential role in tumorigenesis.
Although miR-302 families have been suggested to be tumor repressors in human cancer …

Cancer stem cells, as a subgroup of tumor cells, resemble critical properties of embryonic
stem cells (ESCs) such as self-renewal and maintenance of stemness state. SALL4 and …

Lung cancer is the second most common and the leading cause of cancer related deaths
globally. Tyrosine Kinase Inhibitors (TKIs) are among the common therapeutic strategies in …

Background Esophageal squamous cell carcinoma (ESCC) is the most common histological
type of esophageal cancer, with a poor prognosis. Deregulation of WNT and NOTCH …

There is an inevitable association between cell signaling pathways and tumorigenesis. Wnt
and notch pathways play important roles during development and self-renewal. Beside the …

Abstract Background Bladder cancer (BCa) is a frequent urothelial malignancy with a high
ratio of morbidity and mortality. Various genetic and environmental factors are involved in …