Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence

E Christaki, M Marcou, A Tofarides - Journal of molecular evolution, 2020 - Springer
In recent years, we have seen antimicrobial resistance rapidly emerge at a global scale and
spread from one country to the other faster than previously thought. Superbugs and …

Antibiotic resistance mechanisms in bacteria: relationships between resistance determinants of antibiotic producers, environmental bacteria, and clinical pathogens

E Peterson, P Kaur - Frontiers in microbiology, 2018 - frontiersin.org
Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission

DW Kim, CJ Cha - Experimental & molecular medicine, 2021 - nature.com
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …

Review of antibiotic resistance in China and its environment

M Qiao, GG Ying, AC Singer, YG Zhu - Environment international, 2018 - Elsevier
Antibiotic resistance is a global health crisis linked to increased, and often unrestricted,
antibiotic use in humans and animals. As one of the world's largest producers and …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

[HTML][HTML] Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria

KL Wyres, KE Holt - Current opinion in microbiology, 2018 - Elsevier
Klebsiella pneumoniae is an opportunistic bacterial pathogen known for its high frequency
and diversity of antimicrobial resistance (AMR) genes. In addition to being a significant …

Heavy metal‐induced selection and proliferation of antibiotic resistance: A review

P Vats, UJ Kaur, P Rishi - Journal of applied microbiology, 2022 - academic.oup.com
Antibiotic resistance is recognized as a global threat to public health. The selection and
evolution of antibiotic resistance in clinical pathogens were believed to be majorly driven by …

Next-generation approaches to understand and combat the antibiotic resistome

TS Crofts, AJ Gasparrini, G Dantas - Nature Reviews Microbiology, 2017 - nature.com
Antibiotic resistance is a natural feature of diverse microbial ecosystems. Although recent
studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …

Bacterial multidrug efflux pumps: much more than antibiotic resistance determinants

P Blanco, S Hernando-Amado, JA Reales-Calderon… - Microorganisms, 2016 - mdpi.com
Bacterial multidrug efflux pumps are antibiotic resistance determinants present in all
microorganisms. With few exceptions, they are chromosomally encoded and present a …

What is a resistance gene? Ranking risk in resistomes

JL Martínez, TM Coque, F Baquero - Nature Reviews Microbiology, 2015 - nature.com
Metagenomic studies have shown that antibiotic resistance genes are ubiquitous in the
environment, which has led to the suggestion that there is a high risk that these genes will …