Guanylate-binding protein-1 is a potential new therapeutic target for triple-negative breast cancer

M Quintero, D Adamoski, LM Reis, CFR Ascenção… - BMC cancer, 2017 - Springer
Background Triple-negative breast cancer (TNBC) is characterized by a lack of estrogen and
progesterone receptor expression (ESR and PGR, respectively) and an absence of human …

Treatment outcome of triple-negative breast cancer after 24 months in a tertiary setting: A longitudinal cohort study

OO Ayandipo, OA Ajagbe, MA Ajani… - Journal of Clinical …, 2024 - journals.lww.com
Background: Triple-negative breast cancer (TNBC) is an immunohistochemical type of
breast cancer that lacks estrogen and progesterone receptors and HER2 protein expression …

Nuclear cytoplasmic trafficking of proteins is a major response of human fibroblasts to oxidative stress

NO Baqader, M Radulovic, M Crawford… - Journal of proteome …, 2014 - ACS Publications
We have used a subcellular spatial razor approach based on LC–MS/MS-based proteomics
with SILAC isotope labeling to determine changes in protein abundances in the nuclear and …

Immunohistochemical expression of CDC7 in dentigerous cyst, odontogenic keratocyst and radicular cyst

Z Jaafari-Ashkavandi, AA Tuyeh, S Assar - Acta Medica, 2018 - karolinum.cz
CDC7 is a serine/threonine kinase which has an essential role in initiation of DNA
proliferation and S phase. It increases the invasion and proliferation in many pathologic …

Characterization of Mild Oxidative Stress Response in Human IMR-90 Fibroblasts by Subcellular Quantitative Proteomics

NOA Baqader - 2015 - discovery.ucl.ac.uk
Oxidative stress is a biological state that occurs due to imbalance between reactive oxygen
species (ROS) and the antioxidant system leading to subcellular disturbance. The purpose …