Glucose metabolism: optimizing regenerative functionalities of mesenchymal stromal cells postimplantation

G Luo, P Wosinski, GE Salazar-Noratto… - … Engineering Part B …, 2023 - liebertpub.com
Mesenchymal stromal cells (MSCs) are considered promising candidates for regenerative
medicine applications. Their clinical performance postimplantation, however, has been …

Endo-and exometabolome crosstalk in mesenchymal stem cells undergoing osteogenic differentiation

DSC Bispo, L Michálková, M Correia, CSH Jesus… - Cells, 2022 - mdpi.com
This paper describes, for the first time to our knowledge, a lipidome and exometabolome
characterization of osteogenic differentiation for human adipose tissue stem cells (hAMSCs) …

TRPV4 Activator-Containing CMT-Hy Hydrogel Enhances Bone Tissue Regeneration In Vivo by Enhancing Mitochondrial Health

S Kumar, TK Acharya, S Kumar… - ACS Biomaterials …, 2024 - ACS Publications
Treating different types of bone defects is difficult, complicated, time-consuming, and
expensive. Here, we demonstrate that transient receptor potential cation channel subfamily …

An Intracellular Metabolic Signature as a Potential Donor-Independent Marker of the Osteogenic Differentiation of Adipose Tissue Mesenchymal Stem Cells

DSC Bispo, CSH Jesus, K Romek, IMC Marques… - Cells, 2022 - mdpi.com
This paper describes an untargeted NMR metabolomics study to identify potential
intracellular donor-dependent and donor-independent metabolic markers of proliferation …

Study on the umbilical cord-mesenchymal stem cell manufacturing using clinical-grade culture medium

H Kurogi, T Takijiri, M Sakumoto, M Isogai… - … Engineering Part C …, 2022 - liebertpub.com
Mesenchymal stem/stromal cell (MSC)-based therapies have been gaining increasing
attention owing to their application in various diseases and conditions. In this study, we …