Chromophobe renal cell carcinoma: a review of an uncommon entity
FE Vera‐Badillo, E Conde… - International Journal of …, 2012 - Wiley Online Library
Renal cell carcinoma is the most common neoplasm of the kidney. It is a heterogeneous
disease, comprised of different histological variants with a distinct clinical course, genetics …
disease, comprised of different histological variants with a distinct clinical course, genetics …
Genomic interactions: chromatin loops and gene meeting points in transcriptional regulation
The chromosome conformation capture (3C) technique and its genome-wide applications
('4C') have identified a plethora of distal DNA sequences that are frequently in close spatial …
('4C') have identified a plethora of distal DNA sequences that are frequently in close spatial …
High-resolution DNA copy number and gene expression analyses distinguish chromophobe renal cell carcinomas and renal oncocytomas
MV Yusenko, RP Kuiper, T Boethe, B Ljungberg… - BMC cancer, 2009 - Springer
Background The diagnosis of benign renal oncocytomas (RO) and chromophobe renal cell
carcinomas (RCC) based on their morphology remains uncertain in several cases. Methods …
carcinomas (RCC) based on their morphology remains uncertain in several cases. Methods …
Functional importance of Dicer protein in the adaptive cellular response to hypoxia
JJD Ho, JL Metcalf, MS Yan, PJ Turgeon… - Journal of Biological …, 2012 - ASBMB
The processes by which cells sense and respond to ambient oxygen concentration are
fundamental to cell survival and function, and they commonly target gene regulatory events …
fundamental to cell survival and function, and they commonly target gene regulatory events …
Regulation of endocytosis via the oxygen-sensing pathway
Tumor hypoxia is associated with disease progression, resistance to conventional cancer
therapies and poor prognosis,. Hypoxia, by largely unknown mechanisms, leads to …
therapies and poor prognosis,. Hypoxia, by largely unknown mechanisms, leads to …
A novel molecular signature identifies mixed subtypes in renal cell carcinoma with poor prognosis and independent response to immunotherapy
FA Büttner, S Winter, V Stühler, S Rausch… - Genome Medicine, 2022 - Springer
Background Renal cell carcinoma (RCC) is a heterogeneous disease comprising
histologically defined subtypes. For therapy selection, precise subtype identification and …
histologically defined subtypes. For therapy selection, precise subtype identification and …
Identification of genes that promote or antagonize somatic homolog pairing using a high-throughput FISH–based screen
EF Joyce, BR Williams, T Xie, C Wu - PLoS genetics, 2012 - journals.plos.org
The pairing of homologous chromosomes is a fundamental feature of the meiotic cell. In
addition, a number of species exhibit homolog pairing in nonmeiotic, somatic cells as well …
addition, a number of species exhibit homolog pairing in nonmeiotic, somatic cells as well …
Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy
F Branzoli, C Pontoizeau, L Tchara… - Neuro …, 2019 - academic.oup.com
Background Codeletion of chromosome arms 1p and 19q (1p/19q codeletion) highly
benefits diagnosis and prognosis in gliomas. In this study, we investigated the effect of …
benefits diagnosis and prognosis in gliomas. In this study, we investigated the effect of …
Functional nuclear architecture studied by microscopy: present and future
In this review we describe major contributions of light and electron microscopic approaches
to the present understanding of functional nuclear architecture. The large gap of knowledge …
to the present understanding of functional nuclear architecture. The large gap of knowledge …
[HTML][HTML] Pairing and anti-pairing: a balancing act in the diploid genome
The presence of maternal and paternal homologs appears to be much more than just a
doubling of genetic material. We know this because genomes have evolved elaborate …
doubling of genetic material. We know this because genomes have evolved elaborate …