Multistable and dynamic CRISPRi-based synthetic circuits
Gene expression control based on CRISPRi (clustered regularly interspaced short
palindromic repeats interference) has emerged as a powerful tool for creating synthetic gene …
palindromic repeats interference) has emerged as a powerful tool for creating synthetic gene …
Ultrasensitive molecular controllers for quasi-integral feedback
CC Samaniego, E Franco - Cell Systems, 2021 - cell.com
Feedback control has enabled the success of automated technologies by mitigating the
effects of variability, unknown disturbances, and noise. While it is known that biological …
effects of variability, unknown disturbances, and noise. While it is known that biological …
A model for resource competition in CRISPR-mediated gene repression
CRISPR-mediated gene regulation is known for its ability to control multiple targets
simultaneously due to its modular nature: the same dCas9 effector can target different genes …
simultaneously due to its modular nature: the same dCas9 effector can target different genes …
A universal method for sensitive and cell-free detection of CRISPR-associated nucleases
KJ Cox, HKK Subramanian, CC Samaniego… - Chemical …, 2019 - pubs.rsc.org
A multitude of biological applications for CRISPR-associated (Cas) nucleases have
propelled the development of robust cell-based methods for quantitation of on-and off-target …
propelled the development of robust cell-based methods for quantitation of on-and off-target …
Practical differentiation using ultrasensitive molecular circuits
CC Samaniego, G Giordano… - 2019 18th European …, 2019 - ieeexplore.ieee.org
Biological systems compute spatial and temporal gradients with a variety of mechanisms,
some of which have been shown to include integral feedback. In traditional engineering …
some of which have been shown to include integral feedback. In traditional engineering …
Exploring the Frontier of Technological Progress in Plant Biotechnology
A Aggarwal, A Mehta, M Saraswat - 2023 6th International …, 2023 - ieeexplore.ieee.org
Innovative solutions to major issues in agriculture and sustainability are now available
because of the fusion of bio-inspired computing and plant biotechnology. This study …
because of the fusion of bio-inspired computing and plant biotechnology. This study …
[PDF][PDF] Multistable and dynamic CRISPRi-based synthetic circuits
SM Javier, S Yolanda - bioRxiv, 2019 - serval.unil.ch
Gene expression control based on CRISPRi (clustered regularly interspaced short
palindromic repeats interference) has emerged as a powerful tool for creating synthetic gene …
palindromic repeats interference) has emerged as a powerful tool for creating synthetic gene …
[图书][B] Design of Robust Feedback Networks From Ultrasensitive Modules
CEC Samaniego - 2017 - search.proquest.com
Synthetic biology promise to provide solutions to many challenges in energy, agriculture,
and health by reprogramming cells to execute new tasks in the host organism. In order to do …
and health by reprogramming cells to execute new tasks in the host organism. In order to do …
Design of Robust Feedback Networks From Ultrasensitive Modules
CE Cuba Samaniego - 2017 - escholarship.org
Synthetic biology promise to provide solutions to many challenges in energy, agriculture,
and health by reprogramming cells to execute new tasks in the host organism. In order to do …
and health by reprogramming cells to execute new tasks in the host organism. In order to do …