Aromatase inhibitors (AIs) are a key component in the chemoprevention and treatment of
hormone receptor-positive (HR+) breast cancer. While the addition of AI therapy has …

Background For postmenopausal women with hormone-receptor–positive breast cancer, the
most effective duration for adjuvant therapy with an aromatase inhibitor remains unclear …

Late recurrences are a key challenge for patients with early-stage oestrogen receptor-
positive breast cancer, with the risk of disease relapse continuing steadily from 5 to more …

Background Late recurrences in postmenopausal women with hormone receptor-positive
breast cancers remain an important challenge. Avoidance or delayed development of …

Therapies with the continuous administration of anti-hormonal agents in sex-hormone-
dependent malignancies such as prostate and breast carcinomas often lead to the …

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Breast cancer is the most frequently diagnosed cancer and the leading cause of death from
cancer in women worldwide. Breast cancer is a heterogeneous, phenotypically diverse …