Identifying baseline immune-related biomarkers to predict clinical outcome of immunotherapy

S Gnjatic, V Bronte, LR Brunet, MO Butler… - … for immunotherapy of …, 2017 - Springer
As cancer strikes, individuals vary not only in terms of factors that contribute to its occurrence
and development, but as importantly, in their capacity to respond to treatment. While exciting …

Utilizing population variation, vaccination, and systems biology to study human immunology

JS Tsang - Trends in immunology, 2015 - cell.com
The move toward precision medicine has highlighted the importance of understanding
biological variability within and across individuals in the human population. In particular …

Biomarker panels in ischemic stroke

GC Jickling, FR Sharp - Stroke, 2015 - Am Heart Assoc
BNGF indicates B-type neutrotrophic growth factor; BNP, brain natriuretic peptide; CCR7,
chemokine receptor 7; EGFR, epidermal growth factor receptor; IL, interleukin; MCP-1 …

[HTML][HTML] Pre-pregnancy obesity is associated with greater systemic inflammation and increased risk of antenatal depression

L Sominsky, M O'Hely, K Drummond, S Cao… - Brain, Behavior, and …, 2023 - Elsevier
Background Pre-pregnancy obesity is an emerging risk factor for perinatal depression.
However, the underlying mechanisms remain unclear. We investigated the association …

The effects of age and gender on plasma levels of 63 cytokines

A Larsson, L Carlsson, T Gordh, AL Lind… - Journal of …, 2015 - Elsevier
Cytokines play important roles as regulators of cell functions, and over the last decades a
number of cytokine assays have been developed. The aim of the present study was to …

Redefining serological diagnostics with immunoaffinity proteomics

J Walter, Z Eludin, AP Drabovich - Clinical Proteomics, 2023 - Springer
Serological diagnostics is generally defined as the detection of specific human
immunoglobulins developed against viral, bacterial, or parasitic diseases. Serological tests …

[PDF][PDF] The use of luminex assays to measure cytokines

S Khalifian, G Raimondi, G Brandacher - The Journal of investigative …, 2015 - core.ac.uk
Cytokines are small, soluble peptides or proteins that are produced by a variety of cells that
participate in the immune response, including T cells, B cells, macrophages, mast cells …

Psychiatric disorders biochemical pathways unraveled by human brain proteomics

VM Saia-Cereda, JS Cassoli… - European archives of …, 2017 - Springer
Approximately 25% of the world population is affected by a mental disorder at some point in
their life. Yet, only in the mid-twentieth century a biological cause has been proposed for …

[HTML][HTML] Optimization and qualification of an Fc Array assay for assessments of antibodies against HIV-1/SIV

EP Brown, JA Weiner, S Lin, H Natarajan… - Journal of …, 2018 - Elsevier
Abstract The Fc Array is a multiplexed assay that assesses the Fc domain characteristics of
antigen-specific antibodies with the potential to evaluate up to 500 antigen specificities …

Biomarker profile in stable Fontan patients

A Saraf, C De Staercke, I Everitt, A Haouzi… - International journal of …, 2020 - Elsevier
Background As the population of adults with congenital heart disease (CHD) grows,
cardiologists continue to encounter patients with complex anatomies that challenge the …