Role of reductive versus oxidative stress in tumor progression and anticancer drug resistance

KS Chun, DH Kim, YJ Surh - Cells, 2021 - mdpi.com
Redox homeostasis is not only essential for the maintenance of normal physiological
functions, but also plays an important role in the growth, survival, and therapy resistance of …

The influence of oxidative stress on thyroid diseases

J Kochman, K Jakubczyk, P Bargiel, K Janda-Milczarek - Antioxidants, 2021 - mdpi.com
Thyroid diseases, including neoplasms, autoimmune diseases and thyroid dysfunctions, are
becoming a serious social problem with rapidly increasing prevalence. The latter is …

Could glyphosate and glyphosate-based herbicides be associated with increased thyroid diseases worldwide?

RM Romano, JM Oliveira, VM Oliveira… - Frontiers in …, 2021 - frontiersin.org
The increased incidence of thyroid diseases raises a series of questions about what the
main predisposing factors are nowadays. If dietary restriction of iodine was once a major …

Targeting lactate metabolism by inhibiting MCT1 or MCT4 impairs leukemic cell proliferation, induces two different related death-pathways and increases …

E Saulle, I Spinello, MT Quaranta, L Pasquini… - Frontiers in …, 2021 - frontiersin.org
Metabolism in acute myeloid leukemia (AML) cells is dependent primarily on oxidative
phosphorylation. However, in order to sustain their high proliferation rate and metabolic …

The potential of metabolomics in the diagnosis of thyroid cancer

M Coelho, L Raposo, BJ Goodfellow, L Atzori… - International Journal of …, 2020 - mdpi.com
Thyroid cancer is the most common endocrine system malignancy. However, there is still a
lack of reliable and specific markers for the detection and staging of this disease. Fine …

Metabolite signature of human malignant thyroid tissue: A systematic review and meta‐analysis

SA Razavi, B Khorsand, P Salehipour… - Cancer …, 2024 - Wiley Online Library
Background Thyroid cancer (TC) is the predominant malignancy within the endocrine
system. However, the standard method for TC diagnosis lacks the capability to identify the …

Exploring the potential of myo-inositol in thyroid disease management: focus on thyroid cancer diagnosis and therapy

SA Razavi, M Kalari, T Haghzad, F Haddadi… - Frontiers in …, 2024 - frontiersin.org
Thyroid cancer (TC) is a malignancy that is increasing in prevalence on a global scale,
necessitating the development of innovative approaches for both diagnosis and treatment …

[HTML][HTML] Genetic estimation of correlations between circulating glutamine and cancer

K Zhang, H Liang - American journal of cancer research, 2023 - ncbi.nlm.nih.gov
The controversy regarding the causal relationship between circulating glutamine and cancer
risk remains unresolved. Here, we aim to assess the causal impact of glutamine on the risk …

Systematic review of NMR-based metabolomics practices in human disease research

K Huang, N Thomas, PR Gooley, CW Armstrong - Metabolites, 2022 - mdpi.com
Nuclear magnetic resonance (NMR) spectroscopy is one of the principal analytical
techniques for metabolomics. It has the advantages of minimal sample preparation and high …

[HTML][HTML] Toward systems-level metabolic analysis in endocrine disorders and cancer

A Lakhani, YE Kang, JO Park - Endocrinology and …, 2023 - synapse.koreamed.org
Metabolism is a dynamic network of biochemical reactions that support systemic
homeostasis amidst changing nutritional, environmental, and physical activity factors. The …