Marburg virus (MARV) is a member of the filovirus family that causes hemorrhagic disease
with high case fatality rates. MARV is on the priority list of the World Health Organization for …

Zaire Ebola virus (EBOV) is a member of the Filoviridae family. Infection with EBOV causes
Ebola virus disease (EVD) characterized by excessive inflammation, lymphocyte death …

Ebola virus disease is a severe hemorrhagic fever with a high fatality rate. We investigate
transcriptome profiles at 3 h, 1 day, and 7 days after vaccination with Ad26. ZEBOV and MVA …

Gene expression profiling has helped tremendously in the understanding of biological
processes and diseases. However, interpreting processed data to gain insights into …

Remarkable potency has been demonstrated for mRNA vaccines in reducing the global
burden of the ongoing COVID-19 pandemic. An alternative form of the mRNA vaccine is the …

Ebola virus disease (EVD) is an acute viral hemorrhagic fever disease causing thousands of
deaths. The large Ebola outbreak in 2014–2016 posed significant threats to global public …

Vaccines are needed to disrupt or prevent continued outbreaks of filoviruses in humans
across Western and Central Africa, including outbreaks of Marburg virus (MARV). As part of …

Background During the last decade Ebola virus has caused several outbreaks in Africa. The
recombinant vesicular stomatitis virus-vectored Zaire Ebola (rVSVΔG-ZEBOV-GP) vaccine …

The vectored Ebola vaccine rVSVΔG-ZEBOV-GP elicits protection against Ebola Virus
Disease (EVD). In a study of forty-eight healthy adult volunteers who received either the …

Abstract Background The filovirus Bundibugyo virus (BDBV) causes severe disease with a
mortality rate of approximately 20%–51%. The only licensed filovirus vaccine in the United …