Exosomes─ nature's lipid nanoparticles, a rising star in drug delivery and diagnostics

R Tenchov, JM Sasso, X Wang, WS Liaw, CA Chen… - ACS …, 2022 - ACS Publications
Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

The exosome journey: from biogenesis to uptake and intracellular signalling

S Gurung, D Perocheau, L Touramanidou… - Cell Communication and …, 2021 - Springer
The use of exosomes in clinical settings is progressively becoming a reality, as clinical trials
testing exosomes for diagnostic and therapeutic applications are generating remarkable …

Membrane rafts: portals for viral entry

I Ripa, S Andreu, JA López-Guerrero… - Frontiers in …, 2021 - frontiersin.org
Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

Electrochemical biosensors in exosome analysis; a short journey to the present and future trends in early-stage evaluation of cancers

E Dezhakam, B Khalilzadeh, M Mahdipour… - Biosensors and …, 2023 - Elsevier
The tumor microenvironment consists of a multiplicity of cells such as cancer cells,
fibroblasts, endothelial cells, and immune cells within the specific parenchyma. It has been …

Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …

Tumor-derived small extracellular vesicles in cancer invasion and metastasis: molecular mechanisms, and clinical significance

C Zhang, C Qin, S Dewanjee, H Bhattacharya… - Molecular Cancer, 2024 - Springer
The production and release of tumor-derived small extracellular vesicles (TDSEVs) from
cancerous cells play a pivotal role in the propagation of cancer, through genetic and …

Protein cargo in extracellular vesicles as the key mediator in the progression of cancer

K Hánělová, M Raudenská, M Masařík… - Cell Communication and …, 2024 - Springer
Exosomes are small vesicles of endosomal origin that are released by almost all cell types,
even those that are pathologically altered. Exosomes widely participate in cell-to-cell …

Applications of mesenchymal stem cell-exosome components in wound infection healing: new insights

A Fakouri, ZS Razavi, AT Mohammed… - Burns & …, 2024 - academic.oup.com
The healing process at a wound is made up of many types of cells, growth factors, the
extracellular matrix, nerves and blood vessels all interacting with each other in complex and …

Exosomics in oral cancer diagnosis, prognosis, and therapeutics–An emergent and imperative non-invasive natural nanoparticle-based approach

A Bano, R Vats, P Yadav, R Bhardwaj - Critical Reviews in Oncology …, 2022 - Elsevier
Exosomes-the natural nanoparticles belonging to heterogeneous vesicles are released via
nearly all sorts of cells, including tumour cells, to oprate intercellular communication …

Plant exosome-like nanoparticles as biological shuttles for transdermal drug delivery

Y Wang, Y Wei, H Liao, H Fu, X Yang, Q Xiang… - Bioengineering, 2023 - mdpi.com
Exosomes act as emerging transdermal drug delivery vehicles with high deformability and
excellent permeability, which can be used to deliver various small-molecule drugs and …