The liver is a unique organ with an abundant regenerative capacity. Therefore, partial
hepatectomy (PHx) or partial liver transplantation (PLTx) can be safely performed. Liver …

Tacrolimus (FK 506) is a macrolide immunosuppressant which possesses similar but more
potent immunosuppressant properties compared with cyclosporin, inhibiting cell-mediated …

As every school child knows, chameleons can regenerate a lost tail. Indeed, regrowth of
appendages is a not uncommon phenomenon among other lower animals. In mammals …

Promoting neurological recovery requires strategies that simultaneously provide protection
to injured neurons and increase the numbers of neurons that extend axons while inducing …

Augmenter of liver regeneration (ALR) is a hepatotrophic protein originally identified by
bioassay in regenerating rat and canine livers following partial hepatectomy and in the …

In this clinicopathological study, we have examined the prevalence of biochemical and
histological graft abnormalities in 116 patients who have lived for longer than five years …

Plasma FK506 was studied in 49 liver, 13 heart, 3 double-lung or heart-lung, and 21 kidney
recipients. The levels were correlated with the drug doses used, kidney function, and liver …

Stem cell therapy has shown promise in treating a variety of pathologies including skin
wounds, but practical applications remain elusive. Here, we demonstrate that endogenous …

Cytotoxicity of liver natural killer cells against regenerating hepatocytes has been reported
as a possible mechanism of regeneration failure in fulminant hepatitis. An augmenter of liver …

In cultured cells, growth factor-induced phosphorylation of two translation modulators, p70
S6 kinase and eukaryotic initiation factor 4E-binding protein 1 (4E-BP1), is blocked by …