Background Cancer is characterized by the rampant proliferation, growth, and infiltration of
malignantly transformed cancer cells past their normal boundaries into adjacent tissues. It is …

Meningiomas are the most the common primary brain tumors in adults, representing
approximately a third of all intracranial neoplasms. They classically are found to be more …

Nuclear magnetic resonance (NMR) spectroscopy is an important analytical technique in
metabolomics. Because it provides atomic-level detail of small molecules, NMR is …

Background Gliomas are complex tumors with several genetic aberrations and diverse
metabolic programs contributing to their aggressive phenotypes and poor prognoses. This …

Human cancers represent complex structures, which display substantial inter-and intratumor
heterogeneity in their genetic expression and phenotypic features. However, cancers …

Fourier-transform infrared (FT-IR) and Raman spectroscopy are being widely applied as
sensor-based techniques in oncology, particularly in the diagnosis of brain cancers and their …

Cerebral metabolism is tightly regulated and fundamental for healthy neurological function.
There is increasing evidence that alterations in this metabolism may be a precursor and …

Inflammation is a key factor in multiple diseases including primary immune-mediated
inflammatory diseases eg rheumatoid arthritis but also, less obviously, in many other …

Background: Glioblastoma is the most frequent malignant primitive brain tumor in adults. The
treatment includes surgery, radiotherapy, and chemotherapy. During follow-up, combined …

Congenital heart defects are the most common birth anomaly affecting approximately 1% of
births. With improved survival in this population, there is enhanced ability to assess long …