Background: The test-negative design is an increasingly popular approach for estimating
vaccine effectiveness (VE) due to its efficiency. This review aims to examine published test …

Vaccination remains the most effective way to prevent influenza infection, albeit vaccine
effectiveness (VE) varies by year. Compared to other age groups, children and elderly adults …

The threat of novel influenza infections has sparked research efforts to develop subunit
vaccines that can induce a more broadly protective immunity by targeting selected regions of …

Video Abstract BACKGROUND Influenza antivirals improve outcomes in children with
duration of symptoms< 2 days and those at high risk for influenza complications. Real-world …

Influenza is common in healthy children and adolescents and is associated with a high rate
of hospitalization in this group, especially for those< 5 years. Although the WHO has …

Background Influenza is a major preventable infectious respiratory disease. However, there
is little detailed long-term evidence of its associations with PM 2.5 among children. We …

Importance Children with chronic medical conditions are at increased risk of severe
influenza. Uptake of influenza vaccination in children and adolescents with these identified …

Background National guidelines recommend antiviral treatment for children with influenza at
high risk for complications regardless of symptom duration. Little is known about …

OBJECTIVE: We aimed to systematically review literature assessing interventions targeting
influenza vaccine coverage in children with comorbidities and assess the impact on …

Antigenic changes in surface proteins of the influenza virus may cause the emergence of
new variants that necessitate the reformulation of influenza vaccines every year. Universal …