Many cellular functions are regulated by calcium (Ca2+) signals that are generated by
different signaling pathways. One of these is the inositol 1, 4, 5-trisphosphate/calcium …

The atria provide an important contribution to cardiac function. 1, 2 Besides their impact on
ventricular filling, they serve as a volume reservoir, host pacemaker cells and important parts …

The atria provide an important contribution to cardiac function. 1, 2 Besides their impact on
ventricular filling, they serve as a volume reservoir, host pacemaker cells and important parts …

Ionized calcium (Ca2+) is the most versatile cellular messenger. All cells use Ca2+ signals
to regulate their activities in response to extrinsic and intrinsic stimuli. Alterations in cellular …

Atrial fibrillation (AF) is an arrhythmia that can occur as the result of numerous different
pathophysiological processes in the atria. Some aspects of the morphological and …

The molecular mechanisms underlying atrial fibrillation (AF), the most common form of
arrhythmia, are poorly understood and therefore target-specific treatment options remain an …

Studies on control of fluid secretion by an insect salivary gland led to the discovery of inositol
trisphosphate (IP3) and its role in calcium signalling. Many cell stimuli act on receptors that …

A wide range of Ca2+ signalling systems deliver the spatial and temporal Ca2+ signals
necessary to control the specific functions of different cell types. Release of Ca2+ by Ins P 3 …

Vitamin D deficiency has been linked to many human diseases such as Alzheimer's disease
(AD), Parkinson's disease (PD), multiple sclerosis (MS), hypertension and cardiovascular …

Calcium (Ca2+) is a critical regulator of cardiac myocyte function. Principally, Ca2+ is the
link between the electrical signals that pervade the heart and contraction of the myocytes to …