[HTML][HTML] Macrophages at the interface of the co-evolving cancer ecosystem

DJ Kloosterman, L Akkari - Cell, 2023 - cell.com
Macrophages are versatile and heterogeneous innate immune cells undertaking central
functions in balancing immune responses and tissue repair to maintain homeostasis. This …

Bioengineered nanogels for cancer immunotherapy

X Ma, SJ Li, Y Liu, T Zhang, P Xue, Y Kang… - Chemical Society …, 2022 - pubs.rsc.org
Recent years have witnessed increasingly rapid advances in nanocarrier-based
biomedicine aimed at improving treatment paradigms for cancer. Nanogels serve as …

Engineering macrophages for cancer immunotherapy and drug delivery

Y Xia, L Rao, H Yao, Z Wang, P Ning… - Advanced …, 2020 - Wiley Online Library
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …

Mechanisms of immunotherapy resistance: lessons from glioblastoma

CM Jackson, J Choi, M Lim - Nature immunology, 2019 - nature.com
Glioblastoma (GBM) is the deadliest form of brain cancer, with a median survival of less than
2 years despite surgical resection, radiation, and chemotherapy. GBM's rapid progression …

Tailoring materials for modulation of macrophage fate

J Li, X Jiang, H Li, M Gelinsky, Z Gu - Advanced Materials, 2021 - Wiley Online Library
Human immune system acts as a pivotal role in the tissue homeostasis and disease
progression. Immunomodulatory biomaterials that can manipulate innate immunity and …

Current perspectives and trend of nanomedicine in cancer: A review and bibliometric analysis

Z Pei, S Chen, L Ding, J Liu, X Cui, F Li, F Qiu - Journal of Controlled …, 2022 - Elsevier
The limitations of traditional cancer treatments are driving the creation and development of
new nanomedicines. At present, with the rapid increase of research on nanomedicine in the …

Cellular backpacks for macrophage immunotherapy

CW Shields IV, MA Evans, LLW Wang, N Baugh… - Science …, 2020 - science.org
Adoptive cell transfers have emerged as a disruptive approach to treat disease in a manner
that is more specific than using small-molecule drugs; however, unlike traditional drugs …

Hybrid nanomaterials for cancer immunotherapy

J Li, W Lu, Y Yang, R Xiang, Y Ling, C Yu… - Advanced …, 2023 - Wiley Online Library
Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …

Biomaterial-assisted targeted modulation of immune cells in cancer treatment

H Wang, DJ Mooney - Nature materials, 2018 - nature.com
The past decade has witnessed the accelerating development of immunotherapies for
cancer treatment. Immune checkpoint blockade therapies and chimeric antigen receptor …

Macrophages and microglia: the cerberus of glioblastoma

A Buonfiglioli, D Hambardzumyan - Acta neuropathologica …, 2021 - Springer
Glioblastoma (GBM) is the most aggressive and deadliest of the primary brain tumors,
characterized by malignant growth, invasion into the brain parenchyma, and resistance to …