The role of helper T cells in psoriasis

P Hu, M Wang, H Gao, A Zheng, J Li, D Mu… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is a complex, chronic relapsing and inflammatory skin disorder with a prevalence
of approximately 2% in the general population worldwide. Psoriasis can be triggered by …

Current concepts of psoriasis immunopathogenesis

M Vičić, M Kaštelan, I Brajac, V Sotošek… - International Journal of …, 2021 - mdpi.com
Psoriasis is a recurrent, chronic, immune-mediated, systemic inflammatory disease of the
skin, joints, and other organic systems. After atopic dermatitis, chronic stationary psoriasis is …

Scanning the immunopathogenesis of psoriasis

A Chiricozzi, P Romanelli, E Volpe… - International journal of …, 2018 - mdpi.com
Psoriasis is a chronic inflammatory skin disease, the immunologic model of which has been
profoundly revised following recent advances in the understanding of its pathophysiology. In …

The inflammatory response in psoriasis: a comprehensive review

Y Deng, C Chang, Q Lu - Clinical reviews in allergy & immunology, 2016 - Springer
Psoriasis is a chronic inflammatory autoimmune disease characterized by an excessively
aberrant hyperproliferation of keratinocytes. The pathogenesis of psoriasis is complex and …

New insights of T cells in the pathogenesis of psoriasis

Y Cai, C Fleming, J Yan - Cellular & molecular immunology, 2012 - nature.com
Psoriasis is one of the most common immune-mediated chronic, inflammatory skin diseases
characterized by hyperproliferative keratinocytes and infiltration of T cells, dendritic cells …

Inflammation and psoriasis: a comprehensive review

AM Man, MS Orăsan, OA Hoteiuc… - International Journal of …, 2023 - mdpi.com
Psoriasis is an immune-mediated disease with a strong genetic component that brings many
challenges to sick individuals, such as chronic illness, and which has multiple associated …

[HTML][HTML] Molecular dissection of psoriasis: integrating genetics and biology

JT Elder, AT Bruce, JE Gudjonsson, A Johnston… - Journal of Investigative …, 2010 - Elsevier
Psoriasis is a common and debilitating disease of the skin, nails, and joints, with an
acknowledged but complex genetic basis. Early genome-wide linkage studies of psoriasis …

Cellular mechanisms of psoriasis pathogenesis: a systemic review

M Wu, C Dai, F Zeng - Clinical, cosmetic and investigational …, 2023 - Taylor & Francis
Psoriasis is a common inflammatory skin disease characterized by abnormal proliferation of
epidermal keratinocytes and massive infiltration of inflammatory cells. Many kinds of cells …

[HTML][HTML] Serine protease signaling of epidermal permeability barrier homeostasis

JP Hachem, E Houben, D Crumrine, MQ Man… - Journal of investigative …, 2006 - Elsevier
Evidence is growing that protease-activated receptor-2 (PAR-2) plays a key role in epithelial
inflammation. We hypothesized here that PAR-2 plays a central role in epidermal …

T helper cell subsets in clinical manifestations of psoriasis

M Diani, G Altomare, E Reali - Journal of immunology research, 2016 - Wiley Online Library
Psoriasis is a chronic inflammatory skin disease, which is associated with systemic
inflammation and comorbidities, such as psoriatic arthritis and cardiovascular diseases. The …