Dystonia is a neurological condition characterized by abnormal involuntary movements or
postures owing to sustained or intermittent muscle contractions. Dystonia can be the …

Familial colorectal cancer (CRC) is a major public health problem by virtue of its relatively
high frequency. Some 15-20% of all CRCs are familial. Among these, familial adenomatous …

Este artigo analisa a trajetória de construção de políticas públicas para a agricultura familiar
no Brasil, procurando enfatizar as" gerações" ou referenciais de políticas públicas …

Early-onset torsion dystonia is a movement disorder, characterized by twisting muscle
contractures, that begins in childhood. Symptoms are believed to result from altered …

To the Editor: Most cases of Parkinson's disease are considered sporadic and idiopathic,
although there is evidence of familial aggregation, and several monogenic forms have been …

Background Mutations in the GJB2 gene cause one form of nonsyndromic recessive
deafness. Among Mediterranean Europeans, more than 80 percent of cases of …

The CCR5-Δ32 deletion obliterates the CCR5 chemokine and the human immunodeficiency
virus (HIV)–1 coreceptor on lymphoid cells, leading to strong resistance against HIV-1 …

The genetic dissection of complex diseases represents a formidable challenge for modern
human genetics. Recently, it has been suggested that linkage disequilibrium (LD) based …

Since BRCA1, the first major gene responsible for inherited breast cancer, was cloned1,
more than 50 unique mutations have been detected in the germline of individuals with …

Since the completion of the human genome sequencing project, the discovery and
characterization of human genetic variation is a principal focus for future research …