Neurotoxic effects of organophosphorus pesticides and possible association with neurodegenerative diseases in man: A review

M Jokanović - Toxicology, 2018 - Elsevier
In this article the neurotoxic disorders appearing in patients exposed to organophosphorus
pesticides and known mechanisms involved are reviewed. Organophosphorus compounds …

Multiple neurological effects associated with exposure to organophosphorus pesticides in man

M Jokanović, P Oleksak, K Kuca - Toxicology, 2023 - Elsevier
This article reviews available data regarding the possible association of organophosphorus
(OP) pesticides with neurological disorders such as dementia, attention deficit hyperactivity …

Medical treatment of acute poisoning with organophosphorus and carbamate pesticides

M Jokanović - Toxicology letters, 2009 - Elsevier
Organophosphorus compounds (OPs) are used as pesticides and developed as warfare
nerve agents such as tabun, soman, sarin, VX and others. Exposure to even small amounts …

Unequal efficacy of pyridinium oximes in acute organophosphate poisoning

B Antonijevic, MP Stojiljkovic - Clinical medicine & research, 2007 - Marshfield Clinic
The use of organophosphorus pesticides results in toxicity risk to non-target organisms.
Organophosphorus compounds share a common mode of action, exerting their toxic effects …

Pyridinium oximes as cholinesterase reactivators. Structure-activity relationship and efficacy in the treatment of poisoning with organophosphorus compounds

M Jokanovic, M Prostran - Current Medicinal Chemistry, 2009 - ingentaconnect.com
During more than five decades, pyridinium oximes have been developed as therapeutic
agents used in the medical treatment of poisoning with organophosphorus compounds …

Neurotoxic effects in patients poisoned with organophosphorus pesticides

M Jokanović, M Kosanović - Environmental toxicology and pharmacology, 2010 - Elsevier
In this paper we review neurotoxic disorders appearing in patients poisoned with
organophosphorus pesticides. These compounds cause four important neurotoxic effects in …

Current understanding of the application of pyridinium oximes as cholinesterase reactivators in treatment of organophosphate poisoning

M Jokanović, MP Stojiljković - European journal of pharmacology, 2006 - Elsevier
This paper reviews the mechanisms of interaction of organophosphorus compounds with
cholinesterases and clinical signs of acute poisoning. Further, we describe the current …

Acute organophosphate poisoning: 17 years of experience of the National Poison Control Center in Serbia

V Slavica, B Dubravko, J Milan - Toxicology, 2018 - Elsevier
Based on human toxicity studies, by appropriate regulatory decisions, the number of
organophosphates (OP) on Serbian market has reduced significantly over the last two …

Reduced serum butyrylcholinesterase activity indicates severe systemic inflammation in critically ill patients

AR Zivkovic, K Schmidt, A Sigl… - Mediators of …, 2015 - Wiley Online Library
Systemic inflammation is an immune response to a nonspecific insult of either infectious or
noninfectious origin and remains a challenge in the intensive care units with high mortality …

Biochemical responses as early and reliable biomarkers of organophosphate and carbamate pesticides intoxication: A systematic literature review

S Sepahi, S Gerayli, M Delirrad… - … of biochemical and …, 2023 - Wiley Online Library
Inhibition of cholinesterase (ChE) activity has been long considered as the main diagnostic
method of organophosphate (OP) and carbamate pesticides poisoning; however, it has …