Neurotrophic factor BDNF, physiological functions and therapeutic potential in depression, neurodegeneration and brain cancer
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …
Glutamate and GABA homeostasis and neurometabolism in major depressive disorder
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
per the latest WHO report, MDD affects more than 260 million people worldwide. Despite …
Growth factor delivery: Defining the next generation platforms for tissue engineering
Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …
allowing the formation of tissues. Understanding the key requirements for growth factor …
Stress-induced depression and Alzheimer's disease: focus on astrocytes
OV Dolotov, LS Inozemtseva, NF Myasoedov… - International journal of …, 2022 - mdpi.com
Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …
Effects of antidepressant treatment on neurotrophic factors (BDNF and IGF-1) in patients with major depressive disorder (MDD)
A Mosiołek, J Mosiołek, S Jakima, A Pięta… - Journal of clinical …, 2021 - mdpi.com
Major depressive disorder (MDD) remains the subject of ongoing research as a multifactorial
disease and a serious public health problem. There is a growing body of literature focusing …
disease and a serious public health problem. There is a growing body of literature focusing …
Tai chi improves psychoemotional state, cognition, and motor learning in older adults during the COVID-19 pandemic
R Solianik, D Mickevičienė, L Žlibinaitė… - Experimental …, 2021 - Elsevier
The aim of this study was to determine the effect of a 10-week tai chi intervention on
psychoemotional state, cognition, and motor learning in older adults during the COVID-19 …
psychoemotional state, cognition, and motor learning in older adults during the COVID-19 …
COVID-19 affects serum brain-derived neurotrophic factor and neurofilament light chain in aged men: implications for morbidity and mortality
Background and Methods: Severe COVID-19 is known to induce neurological damage
(NeuroCOVID), mostly in aged individuals, by affecting brain-derived neurotrophic factor …
(NeuroCOVID), mostly in aged individuals, by affecting brain-derived neurotrophic factor …
Effects of long-term administration of Multi-Strain Probiotic on circulating levels of BDNF, NGF, IL-6 and mental health in patients with multiple sclerosis: a randomized …
Background: Mental disorders is one of the main causes of disability and lower life
expectancy among patients with Multiple Sclerosis (MS). The present trial aimed to examine …
expectancy among patients with Multiple Sclerosis (MS). The present trial aimed to examine …
Dissecting the relationship between neuropsychiatric and neurodegenerative disorders
Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …
common causes of death in elderly people, which includes progressive neuronal cell death …
Allopregnanolone in mood disorders: Mechanism and therapeutic development
S Chen, L Gao, X Li, Y Ye - Pharmacological Research, 2021 - Elsevier
The neuroactive steroid allopregnanolone (ALLO) is an endogenous positive allosteric
modulator of GABA type A receptor (GABA AR), and the down-regulation of its biosynthesis …
modulator of GABA type A receptor (GABA AR), and the down-regulation of its biosynthesis …