Dengue is an infectious disease caused by dengue virus (DENV). In general, dengue is a
self‐limiting acute febrile illness followed by a phase of critical defervescence, in which …

Background Dengue is a viral disease whose clinical spectrum ranges from unapparent to
severe forms and fatal outcomes. Although dengue death is 99% avoidable, every year …

Background Coagulation mechanisms are reported to be affected in dengue illness and
evidenced by prolonged activated partial thromboplastin time (APTT) and prothrombin time …

Sepsis is accompanied by thrombocytopenia and the severity of the thrombocytopenia is
associated with mortality. This thrombocytopenia is characteristic of disseminated …

In recent decades, the global incidence of dengue has increased. Affected countries have
responded with more effective surveillance strategies to detect outbreaks early, monitor the …

Background Dengue infection can cause a wide spectrum of clinical outcomes. The severe
clinical manifestations occur sufficiently late in the disease course, during day 4–6 of illness …

Recent studies have revealed that tumor-associated macrophages are the most abundant
stromal cells in the tumor microenvironment and play an important role in tumor initiation …

Acute undifferentiated febrile illness (AUFI) has been a diagnostic dilemma in the tropics.
Without accurate point-of-care tests, information on local pathogens and clinical parameters …

Background. Early prediction of severe dengue could significantly assist patient triage and
case management. Methods. We prospectively investigated 7563 children with≤ 3 days of …

Background Improvements in the early diagnosis of dengue are urgently needed, especially
in resource-limited settings where the distinction between dengue and other febrile illnesses …