Multicomponent reactions (MCRs) have emerged as an efficient and eco-safe approach in
organic synthesis. The influential nature of this approach has been well established in the …

This review aims to collate literature work reported by researchers (from 1994 to 2021) to
provide an overview of the available methodologies for the synthesis and diverse …

Pyrazoles are an important class of heterocycles found in a wide range of bioactive
compounds and pharmaceuticals. Pyrazole synthesis often requires hydrazine or related …

A transition metal-free method for de novo construction of diverse sulfonated pyrazoles from
readily available sulfonyl hydrazides, 1, 3-diketones, and sodium sulfinates was established …

The first classical heterocyclic ionic liquid (IL) promoted C–H bond oxidant cross-coupling
reaction for the intramolecular annulation of 5-(aryloxy)-1 H-pyrazole-4-carbaldehydes to …

Sodium ascorbate (SA) was used as a safe catalyst for the synthesis of 5-aminopyrazole-4-
carbonitriles from the one-pot three-component cyclocondensation (3-CC) of aldehydes …

A simple and efficient copper-catalyzed one-pot synthesis of substituted 1, 2, 4-triazoles
through reactions of two nitriles with hydroxylamine has been developed. The protocol uses …

A novel strategy for the cross dehydrogenative coupling (CDC) of acetophenone
hydrazones and aldehydes has been developed for the synthesis of highly substituted …

Indium (III)/silver (I)-catalyzed [2+ 2+ 1] annulation of arylhydrazine hydrochlorides with β-
enamino esters via multicomponent reactions for the construction of diverse and …

Over the last decade, N–N bond formation as a synthetic strategy has emerged as a
powerful key step in the construction of highly valuable heterocycles from easily obtained …