Role of oxidative stress in depression

S Bhatt, AN Nagappa, CR Patil - Drug discovery today, 2020 - Elsevier
Highlights•The Reactive Oxygen Species have an utmost importance in progression of
Depression.•Depression is associated with lowered concentration of anti-oxidants in …

NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets

Y Zhang, P Murugesan, K Huang, H Cai - Nature Reviews Cardiology, 2020 - nature.com
Reactive oxygen species (ROS)-dependent production of ROS underlies sustained
oxidative stress, which has been implicated in the pathogenesis of cardiovascular diseases …

Measurement and clinical significance of biomarkers of oxidative stress in humans

I Marrocco, F Altieri, I Peluso - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

AGE/RAGE in diabetic kidney disease and ageing kidney

XQ Wu, DD Zhang, YN Wang, YQ Tan, XY Yu… - Free Radical Biology …, 2021 - Elsevier
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease that inevitably
progress to end-stage kidney disease. Intervention strategies such as blood glucose control …

Endothelial cell metabolism

G Eelen, P de Zeeuw, L Treps, U Harjes… - Physiological …, 2018 - journals.physiology.org
Endothelial cells (ECs) are more than inert blood vessel lining material. Instead, they are
active players in the formation of new blood vessels (angiogenesis) both in health and (life …

The role of NADPH oxidases and oxidative stress in neurodegenerative disorders

A Tarafdar, G Pula - International journal of molecular sciences, 2018 - mdpi.com
For a number of years, nicotinamide adenine dinucleotide phosphate (NADPH) oxidases
(NOX) was synonymous with NOX2/gp91phox and was considered to be a peculiarity of …

Endothelial dysfunction and angiogenesis impairment in the ageing vasculature

Z Ungvari, S Tarantini, T Kiss, JD Wren… - Nature Reviews …, 2018 - nature.com
Ageing is the main risk factor for the development of cardiovascular diseases. A central
mechanism by which ageing promotes vascular pathologies is compromising endothelial …

Reactive oxygen species and NRF2 signaling, friends or foes in cancer?

R Wang, L Liang, M Matsumoto, K Iwata, A Umemura… - Biomolecules, 2023 - mdpi.com
The imbalance between reactive oxygen species (ROS) production and clearance causes
oxidative stress and ROS, which play a central role in regulating cell and tissue physiology …

ROS: crucial intermediators in the pathogenesis of intervertebral disc degeneration

C Feng, M Yang, M Lan, C Liu, Y Zhang… - Oxidative medicine …, 2017 - Wiley Online Library
Excessive reactive oxygen species (ROS) generation in degenerative intervertebral disc
(IVD) indicates the contribution of oxidative stress to IVD degeneration (IDD), giving a novel …