Liver fibrosis is defined as excessive extracellular matrix deposition and is based on
complex interactions between matrix-producing hepatic stellate cells and an abundance of …

While non-alcoholic fatty liver disease (NAFLD) is highly prevalent (15% to 45%) in modern
societies, only 10% to 25% of cases develop hepatic fibrosis leading to cirrhosis, end-stage …

Background and Aims Hepatic macrophages can be activated by many factors such as gut‐
derived bacterial components and factors released from damaged hepatocytes …

The pathogenesis of nonalcoholic steatohepatitis (NASH) and inflammasome activation
involves sequential hits. The inflammasome, which cleaves pro–interleukin‐1β (pro–IL‐1β) …

J. Neurochem.(2012) 120, 1060–1071. Abstract This study describes the effects of long‐
chain fatty acids on inflammatory signaling in cultured astrocytes. Data show that the …

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the
Western world, and it persists at a high prevalence. NAFLD is characterised by the …

Chronic liver diseases are frequent and potentially life threatening for humans. The
underlying etiologies are diverse, ranging from viral infections, autoimmune disorders, and …

AIM: To compare the effects of four Bifidobacteria strains (Bifidobacteria L66-5, L75-4, M13-4
and FS31-12, originated from normal human intestines) on weight gain, lipid metabolism …

Liver fibrosis is part of the wound-healing response to liver damage of various origins and
represents a major health problem. Although our understanding of the pathogenesis of liver …

Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of the metabolic
syndrome, can progress to steatohepatitis (NASH) and advanced liver disease. Mechanisms …