Developmental neurotoxicity of pyrethroid insecticides: critical review and future research needs

TJ Shafer, DA Meyer, KM Crofton - Environmental health …, 2005 - ehp.niehs.nih.gov
Pyrethroid insecticides have been used for more than 40 years and account for 25% of the
worldwide insecticide market. Although their acute neurotoxicity to adults has been well …

Effects of Deltamethrin on striatum and hippocampus mitochondrial integrity and the protective role of Quercetin in rats

S Gasmi, R Rouabhi, M Kebieche… - … Science and Pollution …, 2017 - Springer
The present work is to evaluate the neurotoxicity induced by pyrethroid insecticide
“Deltamethrin” at 0.32 mg/kg/day in two main regions of the Wistar rat brain (hippocampus …

On the mechanisms of heavy metal-induced neurotoxicity: amelioration by plant products

N Singh, B Sharma - Proceedings of the National Academy of Sciences …, 2021 - Springer
Heavy metals are defined in terms of their atomic weight, chemical properties, density, or
specific gravity as compared to water. Heavy metal-mediated neurotoxicity has become an …

Neurodevelopmental consequences of gestational and lactational exposure to pyrethroids in rats

F Syed, PJ John, I Soni - Environmental toxicology, 2016 - Wiley Online Library
Indiscriminate use of pyrethroids has raised serious health related concerns, especially
about their effects on children. The present study was designed to assess the developmental …

Deltamethrin induced an apoptogenic signalling pathway in murine thymocytes: exploring the molecular mechanism

A Kumar, D Sasmal, N Sharma - Journal of Applied Toxicology, 2014 - Wiley Online Library
Deltamethrin (DLM) is a well‐known pyrethroid insecticide; however, the immunotoxic
effects of DLM on the mammalian system and its mechanism is still unclear. This study has …

Involvement of dopaminergic and serotonergic systems in the neurobehavioral toxicity of lambda-cyhalothrin in developing rats

RW Ansari, RK Shukla, RS Yadav, K Seth, AB Pant… - Toxicology letters, 2012 - Elsevier
In view of extensive uses of lambda-cyhalothrin, a new generation type II synthetic
pyrethroid, human exposure is quite imminent. The present study has therefore been carried …

S100β upregulation: a possible mechanism of deltamethrin toxicity and motor coordination deficits

N Patro, M Shrivastava, S Tripathi, IK Patro - Neurotoxicology and teratology, 2009 - Elsevier
Deltamethrin (DLT) is a type II synthetic pyrethroid with insecticidal properties. It has been
considered safe to humans. Excessive exposure of DLT is being variously reported, recently …

Cypermethrin induces astrocyte damage: Role of aberrant Ca2+, ROS, JNK, P38, matrix metalloproteinase 2 and migration related reelin protein

SK Maurya, J Mishra, VK Tripathi, R Sharma… - Pesticide biochemistry …, 2014 - Elsevier
Cypermethrin is a synthetic type II pyrethroid, derived from a natural pyrethrin of the
chrysanthemum plant. Cypermethrin-mediated neurotoxicity is well studied; however …

[HTML][HTML] Histomorphometric study of testis in deltamethrin treated albino rats

A Kumar, M Nagar - Toxicology reports, 2014 - Elsevier
Deltamethrin, a type II synthetic pyrethroid, has lead to a widespread concern over the
potential adverse effects on human health. Adult Wistar albino rats, weighing 150–200 g …

Impaired structural and functional development of cerebellum following gestational exposure of deltamethrin in rats: role of reelin

K Kumar, N Patro, I Patro - Cellular and molecular neurobiology, 2013 - Springer
Reelin is an extracellular matrix molecule that is involved in the normal development of the
cerebellar lamination, Bergmann glial fibres alignment, Purkinje cell monolayer …