Formulation and optimisation of bedaquiline nanoemulsions for the potential treatment of multi drug resistant tuberculosis in paediatrics using quality by design

TO Ajayi, MS Poka, BA Witika - Scientific Reports, 2024 - nature.com
Bedaquiline is a drug used for the treatment of multidrug-resistant TB in adults and children
that is currently only commercially available in tablet form. The present study was aimed at …

Celastrol-loaded polymeric mixed micelles shows improved antitumor efficacy in 4 T1 bearing xenograft mouse model through spatial targeting

S Gautam, N Singh, D Marwaha, N Rai… - International Journal of …, 2024 - Elsevier
In this study, we have proposed a novel approach that combines hyaluronic acid (HA), folic
acid (FA), and celastrol (CLS) within a polymeric micelle system (CLS-HF/MLs), offering a …

Simultaneous estimation of rutin and donepezil through RP-HPLC: implication in pharmaceutical and biological samples

R Rana, K Mishra, S Tripathi, AK Gupta, AK Tiwari… - Bioanalysis, 2024 - Taylor & Francis
Aim: A HPLC method was developed and validated for the novel combination of rutin (RN)
and donepezil (DNP). Materials & methods: RN and DNP were simultaneously eluted …

Design of Carnitine-Fatty Acids Ionic Liquids Self Nano Emulsifying Systems to Enhance Oral Drug Delivery

R Das - 2024 - search.proquest.com
The solubility and bioavailability of Biopharmaceutics Classification System (BCS) class IV
drugs, characterized by their low solubility and low permeability pose significant challenges …