Serum 25-hydroxyvitamin D and cancer risk: a systematic review of Mendelian randomization studies

T Lawler, S Warren Andersen - Nutrients, 2023 - mdpi.com
Epidemiological studies suggest that higher serum 25-hydroxyvitamin D is associated with
lower risk for several cancers, including breast, prostate, colorectal, and lung cancers. To …

Vitamin D and human health: evidence from Mendelian randomization studies

A Fang, Y Zhao, P Yang, X Zhang… - European Journal of …, 2024 - Springer
We summarized the current evidence on vitamin D and major health outcomes from
Mendelian randomization (MR) studies. PubMed and Embase were searched for original …

RETRACTED: Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian …

E Sofianopoulou, SK Kaptoge, S Afzal… - The Lancet Diabetes & …, 2021 - thelancet.com
Background Randomised trials of vitamin D supplementation for cardiovascular disease and
all-cause mortality have generally reported null findings. However, generalisability of results …

[HTML][HTML] Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study

G Butler-Laporte, T Nakanishi, V Mooser… - PLoS …, 2021 - journals.plos.org
Background Increased vitamin D levels, as reflected by 25-hydroxy vitamin D (25OHD)
measurements, have been proposed to protect against COVID-19 based on in vitro …

Genetic determinants of daytime napping and effects on cardiometabolic health

HS Dashti, I Daghlas, JM Lane, Y Huang… - Nature …, 2021 - nature.com
Daytime napping is a common, heritable behavior, but its genetic basis and causal
relationship with cardiometabolic health remain unclear. Here, we perform a genome-wide …

Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study

D Manousaki, A Harroud, RE Mitchell, S Ross… - PLoS …, 2021 - journals.plos.org
Background Vitamin D deficiency has been associated with type 1 diabetes in observational
studies, but evidence from randomized controlled trials (RCTs) is lacking. The aim of this …

Circulating levels of micronutrients and risk of infections: a Mendelian randomization study

HM Flatby, A Ravi, JK Damås, E Solligård, T Rogne - BMC medicine, 2023 - Springer
Background Micronutrients play an essential role at every stage of the immune response,
and deficiencies can therefore lead to increased susceptibility to infections. Previous …

Mendelian randomization study updates the effect of 25-hydroxyvitamin D levels on the risk of multiple sclerosis

R Wang - Journal of translational medicine, 2022 - Springer
Background Observational studies and previous Mendelian randomization (MR) studies
have shown that genetically low 25-hydroxyvitamin D (25OHD) levels are associated with a …

Association between circulating 25‐hydroxyvitamin D metabolites and periodontitis: Results from the NHANES 2009–2012 and Mendelian randomization study

W Li, Q Zheng, M Xu, C Zeng… - Journal of clinical …, 2023 - Wiley Online Library
Aim This study sought to investigate associations of 25‐hydroxyvitamin D (25 (OH) D)
metabolites with periodontitis and to assess causality using Mendelian randomization (MR) …

Vitamin D-related polymorphisms and vitamin D levels as risk biomarkers of COVID-19 disease severity

AT Freitas, C Calhau, G Antunes, B Araújo… - Scientific reports, 2021 - nature.com
Vitamin D is a fundamental regulator of host defences by activating genes related to innate
and adaptive immunity. Previous research shows a correlation between the levels of vitamin …