Safety and efficacy of B-cell depletion with rituximab for the treatment of systemic sclerosis–associated pulmonary arterial hypertension: a multicenter, double-blind …

RT Zamanian, D Badesch, L Chung… - American journal of …, 2021 - atsjournals.org
Rationale: Systemic sclerosis (SSc)–pulmonary arterial hypertension (PAH) is one of the
most prevalent and deadly forms of PAH. B cells may contribute to SSc pathogenesis …

Infection and pulmonary vascular diseases consortium: United against a global health challenge

SD Oliveira, S Almodóvar, G Butrous… - Pulmonary …, 2024 - Wiley Online Library
Leveraging the potential of virtual platforms in the post‐COVID‐19 era, the Infection and
Pulmonary Vascular Diseases Consortium (iPVDc), with the support of the Pulmonary …

The landscape of noncoding RNA in pulmonary hypertension

L Deng, X Han, Z Wang, X Nie, J Bian - Biomolecules, 2022 - mdpi.com
The transcriptome of pulmonary hypertension (PH) is complex and highly genetically
heterogeneous, with noncoding RNA transcripts playing crucial roles. The majority of RNAs …

Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension

P Chelladurai, C Kuenne, A Bourgeois… - Science Translational …, 2022 - science.org
Phenotypic alterations in resident vascular cells contribute to the vascular remodeling
process in diseases such as pulmonary (arterial) hypertension [P (A) H]. How the molecular …