[HTML][HTML] Role of epigenetics in biology and human diseases
A Moosavi, AM Ardekani - Iranian biomedical journal, 2016 - ncbi.nlm.nih.gov
For a long time, scientists have tried to describe disorders just by genetic or environmental
factors. However, the role of epigenetics in human diseases has been considered from a …
factors. However, the role of epigenetics in human diseases has been considered from a …
Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …
Epigenomic dysregulation in schizophrenia: in search of disease etiology and biomarkers
Schizophrenia is a severe psychiatric disorder with a complex array of signs and symptoms
that causes very significant disability in young people. While schizophrenia has a strong …
that causes very significant disability in young people. While schizophrenia has a strong …
Developmental programming of oxytocin through variation in early-life stress: Four meta-analyses and a theoretical reinterpretation
Despite evidence supporting a role for oxytocin (OT) in regulating social behavior,
surprisingly little is known about how this neuropeptide is calibrated during development …
surprisingly little is known about how this neuropeptide is calibrated during development …
DNA methylation and schizophrenia: current literature and future perspective
Schizophrenia is a neuropsychiatric disorder characterized by dissociation of thoughts, idea,
identity, and emotions. It has no central pathophysiological mechanism and precise …
identity, and emotions. It has no central pathophysiological mechanism and precise …
Methylome-wide association study of schizophrenia: identifying blood biomarker signatures of environmental insults
Importance Epigenetic studies present unique opportunities to advance schizophrenia
research because they can potentially account for many of its clinical features and suggest …
research because they can potentially account for many of its clinical features and suggest …
Epigenetics and ADHD: reflections on current knowledge, research priorities and translational potential
Attention-deficit/hyperactivity disorder (ADHD) is a common and debilitating
neurodevelopmental disorder influenced by both genetic and environmental factors …
neurodevelopmental disorder influenced by both genetic and environmental factors …
DNA methylation links prenatal smoking exposure to later life health outcomes in offspring
Background Maternal smoking during pregnancy is associated with adverse offspring health
outcomes across their life course. We hypothesize that DNA methylation is a potential …
outcomes across their life course. We hypothesize that DNA methylation is a potential …
Methylomic analysis of salivary DNA in childhood ADHD identifies altered DNA methylation in VIPR2
Background Peripheral epigenetic marks hold promise for understanding psychiatric illness
and may represent fingerprints of gene–environment interactions. We conducted an initial …
and may represent fingerprints of gene–environment interactions. We conducted an initial …
Early life adversity, genomic plasticity, and psychopathology
Child maltreatment is associated with an increased risk of psychiatric disorders, and a range
of health problems later in life. Research suggests that adverse events early in life can lead …
of health problems later in life. Research suggests that adverse events early in life can lead …