Bacteriophage therapy in musculoskeletal infections: from basic science to clinical application

T Ferry, J Onsea, T Roussel-Gaillard… - EFORT Open …, 2024 - eor.bioscientifica.com
The treatment of musculoskeletal infections (MSIs), including periprosthetic joint infection
(PJI) and fracture-related infection (FRI), is often complicated by biofilm-related challenges …

Microbial Persistence, Replacement and Local Antimicrobial Therapy in Recurrent Bone and Joint Infection

BC Young, M Dudareva, MP Vicentine, AJ Hotchen… - Antibiotics, 2023 - mdpi.com
We report microbiological results from a cohort of recurrent bone and joint infection to define
the contributions of microbial persistence or replacement. We also investigated for any …

Comparative analysis of pathogen distribution in patients with fracture-related infection and periprosthetic joint infection: a retrospective study

T Ma, J Lyu, J Ma, X Huang, K Chen, S Wang… - BMC musculoskeletal …, 2023 - Springer
Background The purpose of this study is to investigate the microbial patterns of
periprosthetic joint infection (PJI) and fracture-related infection (FRI), and guide for the …

Are There Any Changes in the Causative Microorganisms Isolated in the Last Years from Hip and Knee Periprosthetic Joint Infections? Antimicrobial Susceptibility …

MD Roman, BA Bocea, NIC Ion, AE Vorovenci… - Microorganisms, 2023 - mdpi.com
Background: PJIs following total hip and knee arthroplasty represent severe complications
with broad implications, and with significant disability, morbidity, and mortality. To be able to …

Unraveling the microbiotas and key genetic contexts identified on stone heritage using illumina and nanopore sequencing platforms

Q Li, C Wu, J He, B Zhang - International Biodeterioration & Biodegradation, 2023 - Elsevier
The application of metagenomics uncovering stone-dwelling microbiotas and its functional
capabilities are of great significance for early warning of stone monuments deterioration and …

Risk Factors for Therapeutic Failure and One-Year Mortality in Patients with Intramedullary Nail-Associated Infection after Trochanteric and Subtrochanteric Hip …

B Pfang, MA Villegas García, A Blanco García… - Antibiotics, 2024 - mdpi.com
Despite the implications of trochanteric and subtrochanteric intramedullary (IM) nail infection
for patients with hip fracture, little is known about risk factors for therapeutic failure and …

The Antibacterial Properties of a Silver Multilayer Coating for the Prevention of Bacterial Biofilm Formation on Orthopedic Implants—An In Vitro Study

SWG van Hoogstraten, J Fechter, R Bargon… - Coatings, 2024 - mdpi.com
The prevention of biofilm formation on orthopedic implants is essential, as biofilms are the
main challenge in the effective treatment of periprosthetic joint infection (PJI). A silver …

Assessment of antimicrobial mismatches in empirical treatment in early PJI after aseptic revision arthroplasty

CM Veerman, JHM Goosen, DSC Telgt… - JAC-Antimicrobial …, 2022 - academic.oup.com
Background In early periprosthetic joint infection (PJI),'debridement, antibiotics and implant
retention'(DAIR) is a widely accepted form of treatment. Empirical antimicrobial treatment is …

局部应用万古霉素预防全膝关节置换切口早期感染

李正远, 郝琳, 陈圣洪, 彭凯, 王俊, 尹宗生 - 中国组织工程研究, 2024 - cjter.com
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Periprosthetic Joint Infection as a Socio-Economic Problem of Modern Orthopedics

SA Bozhkova, RM Tikhilov… - Annals of the Russian …, 2023 - vestnikramn.spr-journal.ru
Periprosthetic joint infection is the main social and economic problem of modern orthopedics
with a recurrence rate of chronic forms of up to 23.2–31.5%. The aim of this review is to …