During recent years it has become increasingly clear that classical neurotransmitters such
as monoamines and the amino acids glutamate and GABA affect the development and …

Recently, cholinergic afferents to cerebral cortex have met renewed attention regarding the
regulation of plasticity as well as cognitive processing. My laboratory has developed a …

The mitogenic effect of muscarinic receptor agonists in glial cells has been characterized in
rat cortical astrocytes and human 132 1N1 astrocytoma cells. The muscarinic receptor …

LITTLE is known about the factors which regulate the growth and development of the
mammalian brain. Although proliferation of neuronal cells ceases relatively early in …

The effect of electrolytic lesions of the neonatal forebrain on the morphogenesis of the
mouse neocortex has been examined. Balb/C mice were lesioned unilaterally within 24 h of …

Methylmercury (MeHg) affects several parameters of cholinergic function. These alterations
are thought to play a role in MeHg neurotoxicity. In vitro experiments have indicated that …

Acetylcholine and other muscarinic agonists stimulate the proliferation of rat cortical
astrocytes and 132 1N1 human astrocytoma cells by activating muscarinic m3 cholinergic …

In utero alcohol exposure can lead to fetal alcohol spectrum disorders, characterized by
cognitive and behavioral deficits. In vivo and in vitro studies have shown that ethanol alters …

Mechanisms triggering the commitment of pluripotent bone marrow stem cells to
differentiated lineages such as mononuclear macrophages or multinucleated …

Infants with neonatal cholestasis are prone to neurodevelopmental deficits, however, the
underlying pathogenesis is unclear. Lipid malabsorption and accumulation of potentially …