Oxidative stress and new pathogenetic mechanisms in endothelial dysfunction: potential diagnostic biomarkers and therapeutic targets

MG Scioli, G Storti, F D'Amico… - Journal of Clinical …, 2020 - mdpi.com
Cardiovascular diseases (CVD), including heart and pathological circulatory conditions, are
the world's leading cause of mortality and morbidity. Endothelial dysfunction involved in …

The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles

P Lacolley, V Regnault, A Nicoletti, Z Li… - Cardiovascular …, 2012 - academic.oup.com
Vascular smooth muscle cells (VSMCs) are the stromal cells of the vascular wall, continually
exposed to mechanical signals and biochemical components generated in the blood …

Regulation of the MIR155 host gene in physiological and pathological processes

TS Elton, H Selemon, SM Elton, NL Parinandi - Gene, 2013 - Elsevier
MicroRNAs (miRNAs), a family of small nonprotein-coding RNAs, play a critical role in
posttranscriptional gene regulation by acting as adaptors for the miRNA-induced silencing …

60 years of neuroendocrinology: redefining neuroendocrinology: stress, sex and cognitive and emotional regulation

BS McEwen, JD Gray, C Nasca - Journal of endocrinology, 2015 - joe.bioscientifica.com
The discovery of steroid hormone receptors in brain regions that mediate every aspect of
brain function has broadened the definition of 'neuroendocrinology'to include the reciprocal …

[HTML][HTML] Potential role of ACE2-related microRNAs in COVID-19-associated nephropathy

A Widiasta, Y Sribudiani, H Nugrahapraja… - Non-coding RNA …, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is responsible
for coronavirus disease (COVID-19), potentially have severe kidney adverse effects. This …

Gene expression profiling reveals renin mRNA overexpression in human hypertensive kidneys and a role for microRNAs

FZ Marques, AE Campain, M Tomaszewski… - …, 2011 - Am Heart Assoc
The kidney has long been invoked in the etiology of essential hypertension. This could
involve alterations in expression of specific genes and microRNAs (miRNAs). The aim of the …

Impact of microRNAs on ischemic stroke: from pre-to post-disease

G Li, KC Morris-Blanco, MS Lopez, T Yang… - Progress in …, 2018 - Elsevier
Stroke is the number one cause of neurological dysfunction in adults and has a heavy
socioeconomic burden worldwide. The etiological origins of ischemic stroke and resulting …

MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis

M Hulsmans, DD Keyzer, P Holvoet - The FASEB Journal, 2011 - Wiley Online Library
ABSTRACT A primary event in atherogenesis is the infiltration of activated inflammatory cells
into the arterial wall. There they secrete reactive oxygen species and oxidize lipoproteins …

Exercise training-induced changes in microRNAs: beneficial regulatory effects in hypertension, type 2 diabetes, and obesity

AC Improta Caria, CKV Nonaka, CS Pereira… - International journal of …, 2018 - mdpi.com
MicroRNAs are small non-coding RNAs that regulate gene expression post-transcriptionally.
They are involved in the regulation of physiological processes, such as adaptation to …

Microvesicles/exosomes as potential novel biomarkers of metabolic diseases

G Müller - Diabetes, metabolic syndrome and obesity: targets and …, 2012 - Taylor & Francis
Biomarkers are of tremendous importance for the prediction, diagnosis, and observation of
the therapeutic success of common complex multifactorial metabolic diseases, such as type …