Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Strategies and Progress of Raman Technologies for Cellular Uptake Analysis of the Drug Delivery Systems

Y Liu, M Li, H Liu, C Kang, X Yu - International Journal of …, 2023 - Taylor & Francis
Nanoparticle (NP)-based drug delivery systems have the potential to significantly enhance
the pharmacological and therapeutic properties of drugs. These systems enhance the …

Label-free evaluation of maturation and hepatotoxicity of human iPSC-derived hepatocytes using hyperspectral Raman imaging

M Li, Y Ueyama-Toba, M Lindley, G Kongklad… - Analytical …, 2023 - ACS Publications
To promote the clinical application of human induced pluripotent stem cell (hiPSC)-derived
hepatocytes, a method capable of monitoring regenerative processes and assessing …

Noise learning of instruments for high-contrast, high-resolution and fast hyperspectral microscopy and nanoscopy

H He, M Cao, Y Gao, P Zheng, S Yan, JH Zhong… - Nature …, 2024 - nature.com
The low scattering efficiency of Raman scattering makes it challenging to simultaneously
achieve good signal-to-noise ratio (SNR), high imaging speed, and adequate spatial and …

P-ring: The conserved nature of phosphorus enriched cells in seedling roots of distantly related species

A Acharya, TC Pesacreta - Plant Signaling & Behavior, 2023 - Taylor & Francis
Plants require sunlight, carbon dioxide, water and mineral ions for their growth and
development. Roots in vascular plants sequester water and ions from soil and transport …

Lipid droplets as cell fate determinants in skeletal muscle

J Chen, JF Markworth, C Ferreira, C Zhang… - Trends in Endocrinology …, 2024 - cell.com
Lipid droplets (LDs) are dynamic organelles that communicate with other cellular
components to orchestrate energetic homeostasis and signal transduction. In skeletal …

Label-Free Raman Spectroscopy for Assessing Purity and Maturation of hiPSC-Derived Cardiac Tissue

J Li, M Li, Y Nawa, Y Liu, K Bando, Y Hua… - Analytical …, 2024 - ACS Publications
I. Background: Human induced pluripotent stem cell (hiPSC) derived cardiomyocytes (CMs)
have been utilized in drug toxicity evaluation, drug discovery, and treating heart failure …

Raman microscopy of cryofixed biological specimens for high-resolution and high-sensitivity chemical imaging

K Mizushima, Y Kumamoto, S Tamura… - Science …, 2024 - science.org
Raman microscopy is an emerging molecular imaging technology, yet its signal-to-noise
ratio (SNR) in measurements of biological specimens is severely limited because of the …

[HTML][HTML] Microscopic water dispersion and hydrogen-bonding structures in margarine spreads with Raman hyperspectral imaging and machine learning

JN Taylor, K Bando, S Tsukagoshi, L Tanaka, K Fujita… - Food Chemistry, 2025 - Elsevier
Margarine, a water-in-oil (W/O) emulsion, offers advantages such as lower costs in
comparison to similar products, but large amounts of saturated fats pose health risks …

Seeing beyond Labels: Optical Technologies Reshaping Cell Culture Monitoring in Biomedicine

M Charconnet, J Plou - ACS Applied Engineering Materials, 2024 - ACS Publications
Label-free optical technologies have transformed cell culture monitoring, offering
noninvasive alternatives that preserve cellular integrity─ a critical factor in biomedical …