Liquid biopsy: general concepts

G Poulet, J Massias, V Taly - Acta cytologica, 2019 - karger.com
Liquid biopsy provides the opportunity of detecting, analyzing and monitoring cancer in
various body effluents such as blood or urine instead of a fragment of cancer tissue. It is …

ctDNA as a cancer biomarker: A broad overview

LS Pessoa, M Heringer, VP Ferrer - Critical reviews in oncology …, 2020 - Elsevier
Circulating tumor DNA (ctDNA) in fluids has gained attention because ctDNA seems to
identify tumor-specific abnormalities, which could be used for diagnosis, follow-up of …

Application of droplet digital PCR to detect the pathogens of infectious diseases

H Li, R Bai, Z Zhao, L Tao, M Ma, Z Ji, M Jian… - Bioscience …, 2018 - portlandpress.com
Polymerase chain reaction (PCR) is a molecular biology technique used to multiply certain
deoxyribonucleic acid (DNA) fragments. It is a common and indispensable technique that …

Emerging digital PCR technology in precision medicine

L Zhang, R Parvin, Q Fan, F Ye - Biosensors and Bioelectronics, 2022 - Elsevier
Digital PCR (dPCR) is built on partitioning reagent to the extent that single template
molecules are amplified and visualized individually, whereby offers higher precision and …

Impact of circulating tumor DNA–based detection of molecular residual disease on the conduct and design of clinical trials for solid tumors

PM Kasi, G Fehringer, H Taniguchi, N Starling… - JCO Precision …, 2022 - ascopubs.org
PURPOSE Earlier detection of cancer recurrence using circulating tumor DNA (ctDNA) to
detect molecular residual disease (MRD) has the potential to dramatically affect cancer …

Liquid biopsy in bladder cancer: State of the art and future perspectives

F Crocetto, B Barone, M Ferro, GM Busetto… - Critical Reviews in …, 2022 - Elsevier
Bladder cancer is the most common malignancy of the urinary tract. Cystoscopy represents
the gold standard in the diagnosis of suspicious bladder lesions. However, the procedure is …

Droplet-based digital PCR and next generation sequencing for monitoring circulating tumor DNA: a cancer diagnostic perspective

M Postel, A Roosen, P Laurent-Puig… - Expert review of …, 2018 - Taylor & Francis
Introduction: Early detection of cancers through the analysis of ctDNA could have a
significant impact on morbidity and mortality of cancer patients. However, using ctDNA for …

Current and emerging applications of droplet digital PCR in oncology

S Olmedillas-López, M García-Arranz… - Molecular diagnosis & …, 2017 - Springer
The clinical management of cancer has evolved in recent years towards more personalized
strategies that require a comprehensive knowledge of the complex molecular features …

[HTML][HTML] Circular RNAs in cancer: limitations in functional studies and diagnostic potential

F Li, Q Yang, AT He, BB Yang - Seminars in cancer biology, 2021 - Elsevier
Circular RNAs (circRNAs) are a large class of noncoding RNAs, generated from a process
called back-splicing, that possess critical regulatory functions in many cellular events. A …

Integrative analysis of multi-omics data for liquid biopsy

G Chen, J Zhang, Q Fu, V Taly, F Tan - British journal of cancer, 2023 - nature.com
The innovation of liquid biopsy holds great potential to revolutionise cancer management
through early diagnosis and timely treatment of cancer. Integrative analysis of different …