Long non‐coding RNA s as an epigenetic regulator in human cancers

Y Kondo, K Shinjo, K Katsushima - Cancer science, 2017 - Wiley Online Library
Recent studies have described the important multiple roles of long non‐coding RNA s (lnc
RNA s) during oncogenic transformation. Because the coding genome accounts for a small …

Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

Application of long noncoding RNAs in osteosarcoma: biomarkers and therapeutic targets

Z Li, P Dou, T Liu, S He - Cellular Physiology and Biochemistry, 2017 - karger.com
Osteosarcoma is the most common primary bone malignancy in children and adolescents.
Although improvements in therapeutic strategies were achieved, the outcome remains poor …

Molecular mechanisms of TUG1 in the proliferation, apoptosis, migration and invasion of cancer cells

H Zhou, L Sun, F Wan - Oncology letters, 2019 - spandidos-publications.com
Long non‑coding RNAs (lncRNAs) are RNA sequences> 200 nucleotides in length that have
no protein‑coding capacity. lncRNAs serve key roles in multiple biological processes, such …

Pathophysiological functions of the lncRNA TUG1

C Guo, Y Qi, J Qu, L Gai, Y Shi… - Current pharmaceutical …, 2020 - ingentaconnect.com
Background: Long non-coding RNAs (lncRNAs) with little or no coding capacity are
associated with a plethora of cellular functions, participating in various biological processes …

Long non-coding RNA implicated in the invasion and metastasis of head and neck cancer: possible function and mechanisms

X Luo, Y Qiu, Y Jiang, F Chen, L Jiang, Y Zhou, H Dan… - Molecular cancer, 2018 - Springer
Head and neck cancer (HNC) ranks as the 6th most common malignancy across the world.
Metastasis is a hallmark of cancer, primarily contributing to the relapse and poor prognosis …

[HTML][HTML] LncRNA TUG1 promotes cell proliferation and suppresses apoptosis in osteosarcoma by regulating miR-212-3p/FOXA1 axis

C Xie, B Chen, B Wu, J Guo, Y Cao - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Background LncRNA taurine upregulated gene 1 (TUG1) was reported to act as a possible
oncogene in osteosarcoma (OS) development. However, the underlying molecular basis of …

Predicting human lncRNA-disease associations based on geometric matrix completion

C Lu, M Yang, M Li, Y Li, FX Wu… - IEEE journal of …, 2019 - ieeexplore.ieee.org
Recently, increasing evidences reveal that dysregulations of long non-coding RNAs
(lncRNAs) are relevant to diverse diseases. However, the number of experimentally verified …

[HTML][HTML] LncRNA ADAMTS9-AS2 inhibits cell proliferation and decreases chemoresistance in clear cell renal cell carcinoma via the miR-27a-3p/FOXO1 axis

E Song, L Xing, L Wang, W Song, D Li, Y Wang… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Accumulating evidence reveals the principal role of long noncoding RNAs in the
progression of clear cell renal cell carcinoma (ccRCC). However, little is known about the …

Polydatin inhibits proliferation and promotes apoptosis of doxorubicin-resistant osteosarcoma through LncRNA TUG1 mediated suppression of Akt signaling

T Hu, Z Fei, H Su, R Xie, L Chen - Toxicology and applied pharmacology, 2019 - Elsevier
Background Development of doxorubicin-resistance is the main difficulty for osteosarcoma
treatment. LncRNA Taurine upregulated gene 1 (TUG1) has been identified as oncogenic …