Arteriovenous malformations are a vascular anomaly typically present at birth, characterized
by an abnormal connection between an artery and a vein (bypassing the capillaries). These …

Formulated as a group effort of the stroke community, the transforming concept of the
neurovascular unit (NVU) depicts the structural and functional relationship between brain …

Brain arteriovenous malformations (AVMs) are a disorder wherein abnormal, enlarged blood
vessels connect arteries directly to veins, without an intervening capillary bed. AVMs are one …

Patients with brain arteriovenous malformation (bAVM) are at risk of intracranial hemorrhage
(ICH). Overall, bAVM accounts for 25% of hemorrhagic strokes in adults< 50 years of age …

Arteriovenous malformations (AVMs) are abnormal connections of vessels that shunt blood
directly from arteries into veins. Rupture of brain AVMs (bAVMs) can cause life-threatening …

Port-wine birthmarks (PWBs) are caused by somatic, mosaic mutations in the G protein
guanine nucleotide binding protein alpha subunit q (GNAQ) and are characterized by the …

The formation of vascular networks consisting of arteries, capillaries, and veins is vital in
embryogenesis. It is also crucial in adulthood for the formation of a functional vasculature …

CNS vascular malformation is an umbrella term that encompasses a wide variety of
pathologies, with a wide range of therapeutic and diagnostic importance. This range spans …

Increased soluble endoglin (sENG) has been observed in human brain arteriovenous
malformations (bAVMs). In addition, the overexpression of sENG in concurrence with …

Extracranial arteriovenous malformations (AVMs) are regarded as rare diseases and are
prone to complications such as pain, bleeding, relentless growth, and high volume of …