Sleep problems in chronic inflammatory diseases: prevalence, treatment, and new perspectives: a narrative review

M Ditmer, A Gabryelska, S Turkiewicz… - Journal of Clinical …, 2021 - mdpi.com
Epidemiological studies have shown that individuals with sleep problems are at a greater
risk of developing immune and chronic inflammatory diseases. As sleep disorders and low …

Circadian control of pain and neuroinflammation

JP Segal, KA Tresidder, C Bhatt, I Gilron… - Journal of …, 2018 - Wiley Online Library
The importance of a neuroinflammatory response to the development and maintenance of
inflammatory and neuropathic pain have been highlighted in recent years. Inflammatory …

Sleep abnormalities in multiple sclerosis

GK Sakkas, CD Giannaki, C Karatzaferi… - Current treatment options …, 2019 - Springer
Purpose of review This review summarizes the most well-documented sleep disorders seen
in patients with multiple sclerosis (MS), with a special focus on the impact on quality of life …

Central fatigue in multiple sclerosis: a review of the literature

P Newland, A Starkweather… - The journal of spinal cord …, 2016 - Taylor & Francis
Concept: Fatigue is a major concern for patients with multiple sclerosis (MS). A clear
definition of MS-related fatigue is a prerequisite for appropriate instruments for fatigue …

Western lifestyle and immunopathology of multiple sclerosis

O Matveeva, JFJ Bogie, JJA Hendriks… - Annals of the New …, 2018 - Wiley Online Library
There is increasing evidence for a sudden and unprecedented rise in the incidence of
multiple sclerosis (MS) in Westernized countries over the past decades, emphasizing the …

Melatonin acts as antioxidant and improves sleep in MS patients

M Adamczyk-Sowa, K Pierzchala, P Sowa… - Neurochemical …, 2014 - Springer
The relationship between the prevalence of multiple sclerosis (MS) and sunlight's ultraviolet
radiation was proved. Oxidative stress plays a role in the pathogenic traits of MS. Melatonin …

[PDF][PDF] Influence of melatonin supplementation on serum antioxidative properties and impact of the quality of life in multiple sclerosis patients

M Adamczyk-Sowa, K Pierzchala, P Sowa… - J Physiol …, 2014 - researchgate.net
The relationship between the prevalence of multiple sclerosis (MS) and sunlight's ultraviolet
radiation was proved. Oxidative stress plays a role in the pathogenic traits of MS. Melatonin …

Therapeutic approaches to insomnia and fatigue in patients with multiple sclerosis

M Drerup, A Roth, A Kane… - Nature and science of …, 2021 - Taylor & Francis
The prevalence of sleep disorders in individuals with multiple sclerosis (MS) is 3–5 times
higher compared to the general population. Insomnia Disorder, defined as difficulty falling …

Demyelination in multiple sclerosis: reprogramming energy metabolism and potential PPARγ agonist treatment approaches

A Vallée, Y Lecarpentier, R Guillevin… - International journal of …, 2018 - mdpi.com
Demyelination in multiple sclerosis (MS) cells is the site of several energy metabolic
abnormalities driven by dysregulation between the opposed interplay of peroxisome …

Sleep disturbance and fatigue in multiple sclerosis: A systematic review and meta-analysis

JJ Bhattarai, KS Patel, KM Dunn… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Sleep disturbance is common in people with multiple sclerosis and may worsen fatigue;
however, the assessment of sleep-fatigue relationships varies across studies. To better …