Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the
importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health …

Evidence suggests that adjunctive psychosocial intervention for the treatment of pediatric
bipolar spectrum disorders (BPSDs) is effective, feasible, and highly accepted as both an …

Introduction No systematic review has estimated the consistency and the magnitude of the
risk of developing bipolar disorder I-II (BD-I/II) in individuals at clinical high risk for bipolar …

Lipidomics has become a pivotal tool in biomarker discovery for the diagnosis of psychiatric
illnesses. However, the composition and quantitative analysis of peripheral lipids in female …

The diagnostic criteria for obsessive-compulsive disorder (OCD) have undergone minor
changes in DSM-5 yet a major turnaround intervened in the overarching categorical …

Background Given the likelihood of progressive illness in bipolar disorder (BD), it is
important to understand the benefits and risks of interventions administered early in illness …

Transitioning to bipolar disorder: A systematic review of pr... : Current Opinion in Psychiatry
Transitioning to bipolar disorder: A systematic review of prospective high-risk studies : Current …

Although early intervention may help prevent the progression of bipolar disorder, there are
some controversies over early pharmacological intervention. In this study, we recruited 40 …

Objectives Subthreshold manic symptoms (subM) are a risk factor for the onset and
recurrence of bipolar disorder (BD). Individuals with subM may benefit from preventive …

The current bipolar disorder treatment guidelines focus mainly on the prevention of
recurrence and stabilization of acute mood episodes while neglecting outcomes related to …