Natural organic and inorganic–hydroxyapatite biopolymer composite for biomedical applications

S Sathiyavimal, S Vasantharaj, F LewisOscar… - Progress in Organic …, 2020 - Elsevier
Regenerative medicine is becoming a fast-growing technique in today's scenario for
biomedical advancement. Researchers around the globe has suggested the involvement of …

Pathogenesis of implant-associated infection: the role of the host

W Zimmerli, P Sendi - Seminars in immunopathology, 2011 - Springer
Implanted devices are mainly used to improve impaired function or to replace missing
anatomic structures. They are made of synthetic material or devitalized biological structures …

The shape and size of hydroxyapatite particles dictate inflammatory responses following implantation

F Lebre, R Sridharan, MJ Sawkins, DJ Kelly… - Scientific reports, 2017 - nature.com
The extent of regeneration following biomaterial implantation is dependent on the
microenvironment surrounding the implant. Since implant composition can have a profound …

Inflammatory cell response to calcium phosphate biomaterial particles: an overview

F Velard, J Braux, J Amedee, P Laquerriere - Acta biomaterialia, 2013 - Elsevier
Bone is a metabolically active and highly organized tissue consisting of a mineral phase of
hydroxyapatite (HA) and amorphous calcium phosphate (CaP) crystals deposited in an …

Sequentially-crosslinked biomimetic bioactive glass/gelatin methacryloyl composites hydrogels for bone regeneration

J Zheng, F Zhao, W Zhang, Y Mo, L Zeng, X Li… - Materials Science and …, 2018 - Elsevier
In recent years, gelatin-based composites hydrogels have been intensively investigated
because of their inherent bioactivity, biocompatibility and biodegradability. Herein, we …

Addressing the osteoporosis problem—multifunctional injectable hybrid materials for controlling local bone tissue remodeling

A Gilarska, A Hinz, M Bzowska, G Dyduch… - … Applied Materials & …, 2021 - ACS Publications
Novel multifunctional biomimetic injectable hybrid systems were synthesized. The
physicochemical as well as biological in vitro and in vivo tests demonstrated that they are …

Hydroxyapatite or fluorapatite—which bioceramic is better as a base for the production of bone scaffold?—A comprehensive comparative study

P Kazimierczak, J Wessely-Szponder, K Palka… - International Journal of …, 2023 - mdpi.com
Hydroxyapatite (HAP) is the most common calcium phosphate ceramic that is used in
biomedical applications, eg, as an inorganic component of bone scaffolds. Nevertheless …

Effect of strontium-substituted biphasic calcium phosphate on inflammatory mediators production by human monocytes

E Buache, F Velard, E Bauden, C Guillaume, E Jallot… - Acta biomaterialia, 2012 - Elsevier
Calcium phosphate materials are widely used as bone substitutes because of their
properties close to those of the mineral phase of bones. Nevertheless, after several months …

In vivo and in vitro evaluation of hydroxyapatite nanoparticle morphology on the acute inflammatory response

S Pujari-Palmer, S Chen, S Rubino, H Weng, W Xia… - Biomaterials, 2016 - Elsevier
Biomedical implants have been widely used in bone repair applications. However,
nanosized degradation products from these implants could elicit an inflammatory reaction …

Neutrophil elastase modulates cytokine expression: contribution to host defense against Pseudomonas aeruginosa-induced pneumonia

R Benabid, J Wartelle, L Malleret, N Guyot… - Journal of Biological …, 2012 - ASBMB
There is accumulating evidence that following bacterial infection, the massive recruitment
and activation of the phagocytes, neutrophils, is accompanied with the extracellular release …