Drugs are prescribed to manage or prevent symptoms and diseases, but may sometimes
cause unexpected toxicity to muscles. The symptomatology and clinical manifestations of the …

Introduction: Statins remain among the most frequently prescribed drugs and constitute a
cornerstone in the prevention of cardiovascular disease. However, muscle symptoms are …

Objective To assess the benefits and harms of lipid-lowering therapies used to prevent or
manage cardiovascular disease including bile acid sequestrants (BAS), ezetimibe, fibrates …

Despite well-defined therapeutic low-density lipoprotein cholesterol (LDL-C) target in the
highest-risk population, low percentage of patients is administered with intensive lipid …

Aim Fermented milk products are suggested as a supplementary therapy to help reduce
blood lipid levels. However, the results of clinical studies are conflicting. Data synthesis This …

Purpose The benefits of statins for ischemic cardio-cerebrovascular diseases are well
known. However, concerns around muscle adverse events still exist. We therefore aimed to …

Introduction Statins have been established as the standard of care for dyslipidemia and
preventing cardiovascular diseases while posing few safety concerns. However …

Lack of time, financial issues, and stressful clinical and educational environments in nursing
studies promote higher intakes of convenience and fast foods loaded with fat and sugar …

Purpose Evolocumab reduced low-density lipoprotein cholesterol (LDL-C) in 12-week trials
in statin-intolerant patients (GAUSS-1 and GAUSS-2); however, the persistence of efficacy …

Atorvastatin calcium (AC)-loaded nanoparticles (NPs) of mean particle diameter< 100 nm
and narrow distribution were prepared and characterized. Their in vivo PK as well as PD …