Tendon injuries are a global health problem that affects millions of people annually. The
properties of tendons make their natural rehabilitation a very complex and long-lasting …

Tendon injuries suffer from a slow healing, often ending up in fibrovascular scar formation,
leading to inferior mechanical properties and even re-rupture upon resumption of daily work …

Tendinopathy is the term used to refer to tendon disorders. Spontaneous adult tendon
healing results in scar tissue formation and fibrosis with suboptimal biomechanical …

Tendon self-renewal is a rare occurrence because of the poor vascularization of this tissue;
therefore, reconstructive surgery using autologous tendon is often performed in severe injury …

Tendon is a fibro-elastic structure that links muscle and bone. Tendon injury can be divided
into two types, chronic and acute. Each type of injury or degeneration can cause substantial …

Clinically relevant in vitro models of human tissue's health and disease are urgently needed
for a better understanding of biological mechanisms essential for the development of novel …

Abstract In his Lissner Award medal lecture in 2000, Stephen Cowin asked the
question:“How is a tissue built?” It is not a new question, but it remains as relevant today as it …

Bioreactors are powerful tools with the potential to model tissue development and disease in
vitro. For nearly four decades, bioreactors have been used to create tendon and ligament …

This review highlights the promise of fiber‐reinforced hydrogel composites (FRHCs) for
augmenting tendon and ligament repair and regeneration. Composed of reinforcing fibers …

Despite the growing clinical use of extracellular matrix (ECM)-based biomaterials for tendon
repair, undesired healing outcomes or complications have frequently been reported. A major …