[HTML][HTML] Apoptotic cell death in disease—Current understanding of the NCCD 2023

I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

[HTML][HTML] Programmed cell death tunes tumor immunity

J Liu, M Hong, Y Li, D Chen, Y Wu, Y Hu - Frontiers in immunology, 2022 - frontiersin.org
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …

[HTML][HTML] From pyroptosis, apoptosis and necroptosis to PANoptosis: A mechanistic compendium of programmed cell death pathways

Y Wang, TD Kanneganti - Computational and structural biotechnology …, 2021 - Elsevier
Pyroptosis, apoptosis and necroptosis are the most genetically well-defined programmed
cell death (PCD) pathways, and they are intricately involved in both homeostasis and …

Fundamental mechanisms of regulated cell death and implications for heart disease

DP Del Re, D Amgalan, A Linkermann… - Physiological …, 2019 - journals.physiology.org
Twelve regulated cell death programs have been described. We review in detail the basic
biology of nine including death receptor-mediated apoptosis, death receptor-mediated …

Immunogenic cell death in cancer therapy: Present and emerging inducers

J Zhou, G Wang, Y Chen, H Wang… - Journal of cellular and …, 2019 - Wiley Online Library
In the tumour microenvironment (TME), immunogenic cell death (ICD) plays a major role in
stimulating the dysfunctional antitumour immune system. Chronic exposure of damage …

Cell death pathways: intricate connections and disease implications

M Kist, D Vucic - The EMBO Journal, 2021 - embopress.org
Various forms of cell death have been identified over the last decades with each relying on a
different subset of proteins for the activation and execution of their respective pathway (s). In …

[HTML][HTML] Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

[HTML][HTML] Innate immune cell death in neuroinflammation and Alzheimer's disease

Y Rajesh, TD Kanneganti - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder molecularly characterized by the
formation of amyloid β (Aβ) plaques and type 2 microtubule-associated protein (Tau) …

[HTML][HTML] Regulated cell death pathways and their roles in homeostasis, infection, inflammation, and tumorigenesis

E Lee, CH Song, SJ Bae, KT Ha, R Karki - Experimental & Molecular …, 2023 - nature.com
Pyroptosis, apoptosis, necroptosis, and ferroptosis, which are the most well-studied
regulated cell death (RCD) pathways, contribute to the clearance of infected or potentially …

[HTML][HTML] The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death

Y Ai, Y Meng, B Yan, Q Zhou, X Wang - Molecular Cell, 2024 - cell.com
Apoptosis, the first regulated form of cell death discovered in mammalian cells, is executed
by caspase-3/7, which are dormant in living cells but become activated by upstream …