Addiction, the most severe form of substance use disorder, is a chronic brain disorder
molded by strong biosocial factors that has devastating consequences to individuals and to …

Answer questions and earn CME/CNE Approximately 30% of all cancer deaths in the United
States are caused by tobacco use and smoking. Cancers of eighteen sites have been …

Practical and clinically focused, Abeloff's Clinical Oncology is a trusted medical reference
book designed to capture the latest scientific discoveries and their implications for cancer …

Background By reducing the amount of nicotine that reaches the brain when a person
smokes a cigarette, nicotine vaccines may help people to stop smoking or to prevent recent …

Clinical trials of nicotine vaccines suggest that they can enhance smoking cessation rates
but do not reliably produce the consistently high serum antibody concentrations required. A …

RNA phages are often used as prototypes for modern recombinant virus-like particle (VLP)
technologies. Icosahedral RNA phage VLPs can be formed from coat proteins (CPs) and are …

Anti-nicotine vaccines may aid smoking cessation via the induction of anti-nicotine
antibodies (Ab) which reduce nicotine entering the brain, and hence the associated reward …

Abstract Background and Aims Nicotine vaccination has been proposed as a possible
treatment to aid smoking cessation. First efficacy results of the nicotine vaccine 3′‐AmNic …

Substance use disorders represent a serious public health and social issue worldwide.
Recent advances in our understanding of the neurobiological basis of the addictive …

A wide range of support is available to help smokers to quit and to aid attempts at harm
reduction, including three first-line smoking cessation medications: nicotine replacement …