HP Lu, L Xun, XS Xie - Science, 1998 - science.org
Enzymatic turnovers of single cholesterol oxidase molecules were observed in real time by monitoring the emission from the enzyme's fluorescent active site, flavin adenine …
RC Petter, JS Salek, CT Sikorski… - Journal of the …, 1990 - ACS Publications
Mono-6-(hexadecylamino)-/3-cyclodextrin (5) and mono-6-(octylamino)-/3-cyclodextrin (4) have been titrated against organic guests (4-nitrophenol, 4-hydroxybenzoic acid …
A flexible and convenient computational method for the simulation of kinetic progress curves has been developed. A mechanism is represented in conventional chemical format with …
XS Xie, HP Lu - Journal of Biological Chemistry, 1999 - ASBMB
Viewing a movie of an enzyme molecule made by molecular dynamics simulation, we see incredible details of molecular motions, be they changes of the conformation or actions …
SV Solomatin, M Greenfeld, S Chu, D Herschlag - Nature, 2010 - nature.com
According to the 'thermodynamic hypothesis', the sequence of a biological macromolecule defines its folded, active (or 'native') structure as a global energy minimum in the folding …
Activation of the small guanosine triphosphatase H-Ras by the exchange factor Son of Sevenless (SOS) is an important hub for signal transduction. Multiple layers of regulation …
M Bollen, W Stalmans - Critical reviews in biochemistry and …, 1992 - Taylor & Francis
Abstract Type 1 protein phosphatases (PP-1) comprise a group of widely distributed enzymes that specifically dephosphorylate serine and threonine residues of certain …