[HTML][HTML] Leprosy: a review of laboratory and therapeutic aspects-Part 2

JC Lastória, MAMM Abreu - Anais brasileiros de dermatologia, 2014 - SciELO Brasil
Leprosy is a chronic infectious condition caused by Mycobacterium leprae (M. leprae). It is
endemic in many regions of the world and a public health problem in Brazil. Additionally, it …

New insights at the interface between leprosy and immune-mediated rheumatic diseases

VA Cruz, CP Albuquerque, MFBR Guimarães… - Frontiers in …, 2023 - frontiersin.org
Leprosy is an infectious and contagious disease of slow evolution, triggered by
Mycobacterium leprae. Arthritis is its third most common manifestation, after cutaneous and …

Unexpectedly high leprosy seroprevalence detected using a random surveillance strategy in midwestern Brazil: A comparison of ELISA and a rapid diagnostic test

MAC Frade, NA de Paula, CM Gomes… - PLoS Neglected …, 2017 - journals.plos.org
Background Leprosy diagnosis is mainly based on clinical evaluation, although this
approach is difficult, especially for untrained physicians. We conducted a temporary …

A novel integrated molecular and serological analysis method to predict new cases of leprosy amongst household contacts

RS Gama, MLM Souza, EN Sarno… - PLoS neglected …, 2019 - journals.plos.org
Background Early detection of Mycobacterium leprae is a key strategy for disrupting the
transmission chain of leprosy and preventing the potential onset of physical disabilities …

[HTML][HTML] Leprosy relapse: a retrospective study on epidemiologic, clinical, and therapeutic aspects at a Brazilian referral center

ACM do Nascimento, DF Dos Santos… - International Journal of …, 2022 - Elsevier
Objectives We aimed to characterize the profile of patients diagnosed with leprosy relapse
and understand the influence of different multidrug therapy (MDT) treatments and initial …

BCG vaccine and leprosy household contacts: protective effect and probability to becoming sick during follow-up

RR Gomes, DE Antunes, DF Dos Santos, EFP Sabino… - Vaccine, 2019 - Elsevier
Abstract Background Immunoprophylaxis with Bacillus Calmette–Guérin (BCG) vaccine is
still the most effective intervention in the prevention of leprosy among household contacts …

[HTML][HTML] ML Flow serological test: complementary tool in leprosy

JOM Montanha, SMT Nardi, FMT Binhardi… - Anais Brasileiros de …, 2023 - SciELO Brasil
Background The evaluation of household contacts of leprosy cases allows the early
diagnosis of new cases. Objective To associate the results of the ML Flow test with the …

Leprosy, a neglected disease that causes a wide variety of clinical conditions in tropical countries

NT Foss, ACF Motta - Memórias do Instituto Oswaldo Cruz, 2012 - SciELO Brasil
Leprosy is an ancient disease that remains endemic and continues to be a major public
health problem in some tropical countries, where it has been internationally recognized as …

[HTML][HTML] Anti-PGL1 salivary IgA/IgM, serum IgG/IgM, and nasal Mycobacterium leprae DNA in individuals with household contact with leprosy

PB e Cabral, JEC Junior, AC de Macedo… - International Journal of …, 2013 - Elsevier
Objectives Leprosy household contacts represent a group at high risk of developing the
disease. The aim of this study was to detect Mycobacterium leprae subclinical infection in …

The oral cavity in leprosy: what clinicians need to know

GA Rodrigues, NP Qualio, LD de Macedo… - Oral …, 2017 - Wiley Online Library
Leprosy is a chronic infectious disease caused by Mycobacterium leprae, a bacillus that has
a tropism for skin and peripheral nerves. Leprosy treatment is based on a multidrug therapy …